This randomized controlled trial (RCT) will compare the efficacy and feasibility and acceptability of a culturally adapted CBT manual with a standard CBT manual, focusing on addressing cultural factors in therapy delivery.
Individuals aged 18 to 65 years
5 years of education
Symptoms of depression and anxiety
Substance use disorder according to DSM-5 criteria as determined by primary care clinician
Significant cognitive impairment (for example, profound learning disability or dementia) as determined by primary care clinician
Active psychosis as determined by their primary care clinician