In France, one in 4500 women is affected by the MayerRokitantskyKüsterHauser (MRKH) syndrome which is characterized by the absence of uterus at birth. Currently, the only solutions for these patients are:
* Gestational surrogacy, prohibited in France * Adoption * Resignation
Uterine transplantation could become a good alternative.
This study is conducted in 10 patients with MRKH type I syndrome, who will be transplanted from a living donor uterus
Being aged between 18 and 38 years old
In stable couple, with a pregnancy project, favorable psychological evaluation
No history of cancer and transfusion
Absence of comorbidity (neurological, nephro-urological pathology, infectious, psychiatric or psychological pathology)
Extreme oligo-astheno-spermia and azoospermia in the husband
History of abdominopelvic surgery excluding uncomplicated appendectomy; vaginal residue not allowing anastomosis
Known thromboembolic risk factor
No Compatibility with the recipient (group, rhesus, HLA)