The purpose of this pilot randomized-controlled trial is to determine whether Fecal Microbiota Transplant (FMT) treatment demonstrates feasibility, acceptability, and prelinary effectiveness among patients with anorexia nervosa (AN). Specifically, the investigators aim to compare changes in weight, gut microbiome, urine, blood biomarkers and mood symptoms between participants receiving the FMT intervention and placebo.
Be 12-17 years-old at time of recruitment
Have capacity to consent
Be assigned female sex at birth (may be gender diverse)
Be active patients in the pediatric ED program at MCH
Exposure to antibiotics within two weeks of study randomization
Initiation of new probiotics / oral nutritional supplements within two weeks of randomization
Active pregnancy
Active psychosis or suicidal ideation
Hamilton Health Sciences Corporation
Lead sponsor
McMaster University
Collaborator
Hamilton Academic Health Sciences Organization
Collaborator