About this trial
The use of FANS has changed the operative landscape of RIRS by allowing continuous active suction-assisted clearance of ablated stone material in real time. Use of fragmentation technique in FANS requires high-energy to reduce stone burden into small fragments, followed by active suction of residual fine material. Dusting with FANS, on the other hand, converts the entire stone volume into sub-millimetre particulate that is continuously suctioned away during lasing potentially offering a more streamlined workflow with potentially less energy usage, reduced mechanical stress on the ureteroscope working channel, and fewer scope withdrawals. The combination of TFL dusting with FANS-assisted real-time evacuation may produce stone-free outcomes equivalent or superior to fragmentation, while offering these additional operative efficiencies.
Whether dusting using TFL with FANS is non-inferior or indeed superior to fragmentation using TFL with FANS in terms of stone-free rate at one month has not been evaluated in prospective randomised trial yet. This study aims to answer that specific question in patients with renal stone less than 2 cm.
Eligibility criteria
Qualifiers
Age ≥18 years
Renal stone(s) confirmed on non-contrast CT KUB
Total stone less than 2cm
Stone amenable to flexible ureterorenoscopy (FURS)
Disqualifiers
Active urinary tract infection (positive urine culture) at time of planned surgery
Anatomical anomalies precluding safe FURS (e.g., infundibular stenosis, severe calyceal diverticulum inaccessible to flexible scope)
Pregnancy or breastfeeding
Prior ipsilateral renal surgery within 3 months of enrollment
Trial design
Treatments tested in this trial
- Dusting
- Fragmentation