Renal Stone

8

Review clinical trials related to Renal Stone. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Fragmentation Vs Dusting With FANS for Renal Stones Less Than 2cm: A Randomized Controlled Study

The use of FANS has changed the operative landscape of RIRS by allowing continuous active suction-assisted clearance of ablated stone material in real time. Use of fragmentation technique in FANS requires high-energy to reduce stone burden into small fragments, followed by active suction of residual fine material. Dusting with FANS, on the other hand, converts the entire stone volume into sub-millimetre particulate that is continuously suctioned away during lasing potentially offering a more streamlined workflow with potentially less energy usage, reduced mechanical stress on the ureteroscope working channel, and fewer scope withdrawals. The combination of TFL dusting with FANS-assisted real-time evacuation may produce stone-free outcomes equivalent or superior to fragmentation, while offering these additional operative efficiencies. Whether dusting using TFL with FANS is non-inferior or indeed superior to fragmentation using TFL with FANS in terms of stone-free rate at one month has not been evaluated in prospective randomised trial yet. This study aims to answer that specific question in patients with renal stone less than 2 cm.

Participants needed: 86
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Bir HospitalUpdated: Jun 30, 2026
Eligibility criteria

Age ≥18 years [+6]

Active urinary tract infection (positive urine culture) at time of planned surge... [+8]

Status: Recruiting

Supervised Endoscopic Tele-controlled Intelligent Lithotripsy

This is a phase I feasibility study to investigate the use of a novel intelligent robotic retrograde intrarenal surgery (RIRS) platform. The TaloStone T1000 RIRS system can manipulate the flexible ureteroscope, with remote control of the instruments (laser fibre or basket) and ureteral access sheath movements. Beyond teleoperation, the TaloStone T1000 RIRS system integrates AI perception models and decision-making algorithms to enable the supervised autonomous execution of critical tasks within the RIRS workflow.

Participants needed: 15
Trial details
Age: 19+Biological sex: AllType: InterventionalSponsor: Chinese University of Hong KongUpdated: Apr 24, 2026Locations: 1
Eligibility criteria

Adult patients >18 years old [+3]

Patients with no preoperative CT imaging available [+7]

Status: Not yet recruiting

Retrograde Intrarenal Surgery Versus Extracorporeal Shockwave Lithotripsy

The study's aim is to determine which treatment modality, either ESWL or RIRS, is more effective in achieving stone clearance for lower calyceal calculi. Investigators hypothesize that retrograde intrarenal surgery is better as compared to extracorporeal shockwave lithotripsy. It will target those patients suffering from kidney stones in lower calyces with sizes up to 1.5 cm in an open-label, randomized controlled trial.

Participants needed: 66
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Sindh Institute of Urology and TransplantationUpdated: Apr 15, 2026Locations: 1
Eligibility criteria

Those patients will be included with lower calyceal renal stones and size up to... [+2]

Untreated Urine culture positive will be excluded [+2]

Status: Recruiting

Erector Spinae Plane Block for Analgesia During ESWL

this study aims to compare between efficacy of erector spinae plane block and conventional multimodal analgesia in Extracorporeal shock wave lithotripsy

Participants needed: 60
Trial details
Age: 21-60Biological sex: AllType: InterventionalSponsor: Sohag UniversityUpdated: Jul 16, 2025Locations: 1
Eligibility criteria

Adult Patients undergoing ESWL with 2-3 cm renal stones [+5]

Coagulopathy or on anticoagulants [+5]

Status: Recruiting

Robotic Flexible Ureteroscopy Versus Standard Flexible Ureteroscopy for Renal Stones

This is a prospective randomized clinical trial which aims to compare the clinical outcomes of robotic flexible ureteroscopy and standard flexible ureteroscopy for the treatment of renal stones.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Chinese University of Hong KongUpdated: May 6, 2025Locations: 1
Eligibility criteria

Age ≥ 18 years old with informed consent [+1]

Patients with abnormal urinary tract (e.g. ileal conduit, neobladder, ureteric s... [+3]

Status: Recruiting

High Versus Low Power Settings During Ureteroscopic Laser Lithotripsy

The primary aim of the study is to compare the operative times following ureteroscopic lithotripsy for renal stones with Thulium Fiber Laser using low and high power settings. Secondary aims are to compare the results of low and high power settings in terms of stone free rates, laser time, laser activation patterns, intraoperative and postoperative complications. Patients ≥ 18 years with renal stones (8-25 mm) scheduled for ureteroscopic lithotripsy at the Day Surgery Clinic at Haukeland University Hospital in Bergen, Norway, are eligible for inclusion in the study. After written consent and inclusion, patients are randomised to laser lithotripsy using either low power settings (Group 1: 4-6 Watt, short pulse mode) or high power settings (Group 2: 16-18 Watt, short pulse mode). The ureteroscopic procedures are performed in general anaesthesia using a standardised technique. All patients are followed up with a low dose CT scan 3 months post endoscopically to assess stone free status as well as a consultation at the outpatient clinic. Results and data for the two randomisation groups are compared according to the aims of the study.

Participants needed: 150
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Haukeland University HospitalUpdated: Mar 5, 2025Locations: 1
Eligibility criteria

Patients ≥ 18 years scheduled for URS lithotripsy for renal stones, 8-25 mm, at...

Concomitant ureteral stone [+3]

Status: Recruiting

Perioperative Parameter and Treatment Outcomes of ECIRS in Asia

This is an observational, international, multicenter, cohort study, prospectively collecting clinical data registry on consecutive patients with urinary stone undergoing ECIRS.

Participants needed: 1,000
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Chinese University of Hong KongUpdated: Aug 23, 2024Locations: 3
Eligibility criteria

Patients with urinary calculi [+2]

Patients who have ECIRS for other conditions, such as urothelial cancer etc. [+2]

Status: Recruiting

Effect of Preoperative Silodosin on Feasibility of Ureteral Access Sheath Insertion

The ureteral access sheath (UAS) is an ancillary device widely used by urologists to facilitate fast, repeatable, and safe access to ureters and collecting systems; improve visibility; reduce the risk of infection by reducing intrarenal pressure; and protect ureters and scopes when extracting multiple stones during surgery. Insertion of ureteric access sheath may be difficult due to tight ureter, so sometimes preoperative stenting might be needed. Silodosin is an α1A adrenoceptor with high affinity and selectivity for the ureteric muscle, which may reduce ureteral spasm. Oral a1-blockers can reduce intraureteral pressure, and may reduce maximal ureteral access sheath insertion force.¹ Preoperative silodosin protects against significant ureteral injury related to UAS insertion during fURS and decreases postoperative pain level. Silodosin premedication might be an effective and safe technique to replace prestenting.²

Participants needed: 2,000
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Al-Azhar UniversityUpdated: Aug 8, 2023Locations: 1
Eligibility criteria

All patients with renal stones who will undergo flexible ureteroscopy and planne...

Paediatric age group (less than 18 year)