General Anesthetics-related Changes in Prefrontal EEG During Pediatric Surgical Anesthesia

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age1-18
SponsorPeking University First Hospital

About this trial

The change profiles of indices derived from pEEG such as phase-amplitude coupling and bicoherence based on individual general anesthetics in children have not been examined in previous literature. Whether those indices have the abilities to predict individual drug-related anesthesia depth in children need to be explored.

Eligibility criteria

Qualifiers

patients aged 0-18 years, American Society of Anesthesiologists Physical Status I-II, scheduled for elective surgery in Peking University First Hospital.

Disqualifiers

Preterm patients;

Height and weight not within the standard ranges for respective ages;

Surgery for head or heart;

Patients with muscular, neurologic or psychiatric diseases;

Trial design

Treatments tested in this trial

  • propofol
  • sevoflurane
  • S-ketamine

Treatment groups

366 Participants
are divided into 3 treatment groups