Genetic Feature of Congenital Hearing Loss in Chinese Population
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 6
SponsorDan Bing
About this trial
Congenital hearing loss, as well as hearing loss present at birth, is one of the most common chronic conditions in children, with a prevalence of permanent bilateral hearing loss of 2.83 per 1000 children of primary school age, which is mainly caused by genetic factors. The goal of this observational study is to learn about novel causative genes in infants with hearing loss in the Chinese population. The main problem it aims to deal with are:
* to present the genetic characteristics of the infant with hearing loss in the Chinese population * to build up a prognostic model base on diverse data.
Participants will be asked to receive audiological tests and collection of the peripheral blood sample.
Eligibility criteria
Qualifiers
Age up to 6 months
Fail in the neonatal hearing screening programs, including oto-acoustic emissions and automated auditory brain stem response
Promise to complete the tests required at baseline and follow-ups by the legal representative
Informed consent by the legal representative
Disqualifiers
Congenital infections related to acquired or congenital hearing loss, including rubella virus, cytomegalovirus, herpes simplex virus, rubella virus, toxoplasma gondii and treponema pallidum infections
Other explicit otologic conditions which could induce hearing loss, including cerumen, otitis media, congenital middle ear abnormalities, microtia and external ear abnormalities
A drug with ototoxicity usage during pregnancy
Other severe congenital anomalies
Trial design
Treatments tested in this trial
- Not listed
Trial groups
50 Participants
are grouped into 1 trial groupLocations
Sponsors and collaborators
Dan Bing
Lead sponsor
Tongji Hospital
Sponsor institution
Source ClinicalTrials.gov