About this trial
Over 20,000 patients a year in the UK get surgery or radiotherapy to cure their prostate cancer. These men then undergo regular check-ups to manage potential side effects and see if cancer recurs so it can be treated quickly. The organisation of these check-ups varies across the country as it is not known which approach is best. The four different established approaches are (i) check-ups performed in hospital outpatients by the same team that provided treatment; (ii) patients seen regularly by their GP with hospital referral as necessary; (iii) planned shared care between general practice and hospital follow up; or (iv) patients supported to provide checks on themselves (self-care) and reaching out to a doctor or a nurse when required. This study will compare these options to establish which is best for patients and makes the best use of the NHS resources.
Eligibility criteria
Qualifiers
Having newly-diagnosed non-metastatic, clinically localised prostate cancer (ICD-10 code C61) in the Cancer Registry between 1 January 2018 and 31 December 2023;
Age 18 or over at diagnosis;
Completed primary curative treatment at an eligible hospital between 1 January 2019 and 31 December 2023 with either: radical radiotherapy +/- hormones, or radical prostatectomy with curative intent +/- lymphadenectomy, or focal therapy, in keeping with local practice;
Alive with no disease progression or metastasis 6 months after the date of completion of primary curative treatment.
Disqualifiers
Men who are treated for metastatic cancer; or receiving palliative prostate cancer care;
Men who have opted out of their data being used as part of national routine data sets will be excluded (https://digital.nhs.uk/services/national-data-opt-out).
Alive;
Have achieved between three to four and a half years of follow up (from completion of initial curative treatment) during the survey period.
Trial design
Treatments tested in this trial
- Hospital based follow up
- Primary care based follow up
- Planned shared care follow up
- Self-management
Treatment groups
Sponsors and collaborators
Imperial College London
Lead sponsor
London School of Hygiene and Tropical Medicine
Collaborator
University of Aberdeen
Collaborator
University of Leeds
Collaborator
Cardiff University
Collaborator
University of Sheffield
Collaborator
University of Southampton
Collaborator
University College, London
Collaborator
Royal Marsden NHS Foundation Trust
Collaborator
North Bristol NHS Trust
Collaborator
Cardiff and Vale University Health Board
Collaborator
Liverpool University Hospitals NHS Foundation Trust
Collaborator
National Institute for Health Research, United Kingdom
Collaborator