The present study aims to evaluate and compare the clinical, radiographic, and biological peri-implant tissue outcomes of platelet-rich fibrin versus probiotics as adjuncts to immediate implant placement combined with subepithelial connective tissue grafting in adults requiring single immediate implant placement.
Adults aged 20 to 45 years.
Systemically healthy patients eligible for implant surgery.
Patients requiring extraction of a single non-restorable tooth indicated for immediate implant placement.
Implant sites located in the maxillary esthetic or para-esthetic zone.
Medically compromised patients or patients with systemic conditions that may contraindicate implant surgery or interfere with healing.
Smokers.
Pregnant or lactating women.
Patients with uncontrolled periodontal disease or poor oral hygiene.