Dental Implant Failed

10

Review clinical trials related to Dental Implant Failed. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Immediate Implant Placement With Subepithelial Connective Tissue Grafting and Probiotics

The present study aims to evaluate and compare the clinical, radiographic, and biological peri-implant tissue outcomes of platelet-rich fibrin versus probiotics as adjuncts to immediate implant placement combined with subepithelial connective tissue grafting in adults requiring single immediate implant placement.

Participants needed: 22
Trial details
Age: 20-45Biological sex: AllType: InterventionalSponsor: Kafrelsheikh UniversityUpdated: May 19, 2026Locations: 1
Eligibility criteria

Adults aged 20 to 45 years. [+7]

Medically compromised patients or patients with systemic conditions that may con... [+9]

Status: Not yet recruiting

Guided Modified Socket Shield With Hyaluronic Acid for Black Triangle Management

The Primary aim of this study will be to evaluate the clinical, esthetic, and radiographic outcomes of hyaluronic acid combined with immediate implant placement using AI-assisted and computer guided modified socket shield technique in maxillary anterior sites exhibiting black triangles.

Participants needed: 32
Trial details
Age: 20-50Biological sex: AllType: InterventionalSponsor: Kafrelsheikh UniversityUpdated: May 15, 2026Locations: 1
Eligibility criteria

Adults (20-50) years old. [+4]

Medically compromised patients and systemic conditions that complicate implant p... [+5]

Status: Recruiting

L-PRF Versus Sticky Bone Grafting of the Jumping Gap in AI-assisted Computer-Guided Socket Shield Immediate Implantation

the rationale of the current study is to address a focused and clinically relevant gap in socket shield therapy: which biologic modality best supports healing of the shield-implant gap when SST is performed under a standardized, digitally guided workflow. The study will compare three shield-implant gap filling modalities: (i) L-PRF alone (without membrane), (ii) sticky tooth (autogenous dentin graft +i- PRF), and (iii) sticky bone (particulate graft + i- PRF) under AI-assisted, patient-specific guided implant placement based on IOS/CBCT superimposition, with CBCT follow-up at immediate, 3 months, and 6 months. The working hypothesis is that biologically active, cohesive composites (sticky tooth and sticky bone) will provide superior hard- and soft-tissue dimensional stability compared with PRF alone by improving space maintenance and early wound stability in the shield-implant gap . The null hypothesis is that there will be no statistically significant differences between the three modalities in radiographic and digitally assessed clinical outcomes over the 6-month follow-up period .

Participants needed: 45
Trial details
Age: 18-45Biological sex: AllType: InterventionalSponsor: Kafrelsheikh UniversityUpdated: Mar 18, 2026Locations: 2
Eligibility criteria

Medically healthy patients according to the American Society of Anesthesiologist... [+3]

Patients belonging to ASA III, ASA IV and ASA V will be excluded. [+5]

Status: Recruiting

Clinical Performance of Dual-cantilevered Single-implant Bridge

The study aims to evaluate the clinical performance (implant and prosthetic survival/ success rates) of a novel implant-supported fixed dental prosthesis design: the dual-cantilevered single implant bridge (T-Bridge) made out of monolithic zirconia bonded to a titanium base abutment (Variobase abutments)

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of BernUpdated: Feb 18, 2026Locations: 1
Eligibility criteria

Age ≥ 20 years [+7]

Any physical or mental disorder that would interfere with the ability to perform... [+5]

Status: Recruiting

Antiseptic Effects on the Dental Implant Internal Surface Microbiome

Soldiers operate in environments that are more likely to lead to oral trauma, risking poor dentition which can directly impact military readiness. Dental restoration can often be accomplished via dental implant insertion. Microbiome-associated complications that result in bone loss, including the micro-leakage of bacterial species proliferating in the dental implant internal cavity, frequently lead to implant failure. Reduction in implant bacterial load may result in a shift of the composition of the microbiome in favor of less pathogenic species, potentially improving dental implant success rates, reducing surgical revisions, and associated cost savings. This study aims to determine how disinfectant gel (hydrogen peroxide or chlorhexidine) insertion into dental implant internal cavities affects implant failure rates, bacterial load and microbiome composition.

Participants needed: 150
Trial details
Phase: Early Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Madigan Army Medical CenterUpdated: Dec 27, 2024Locations: 1
Eligibility criteria

Active duty military [+2]

Tobacco user [+3]

Status: Recruiting

Comparison of Conventional Impressions, Intraoral Scanners and Digital Photogrammetry for Full-arch Implant Prosthesis.

The aim of this clinical trial is to compare implant-supported definitive impressions in edentulous patients (mandible or maxilla) with 4 to 8 osseointegrated implants. The main questions it aims to answer are : The primary outcome of this prospective clinical comparative study is to analyse the precision of a complete-arch impression. The secondary aim is to obtain patient satisfaction with these new types of impression. The different impressions (conventional, intraoral scanner and photogrammetry) will be taken twice on the same patient.

Participants needed: 20
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Centre Hospitalier Universitaire de LiegeUpdated: Aug 26, 2024Locations: 1
Eligibility criteria

edentulous maxilla or mandible with 4 to 8 osseointegrated implants (NobelBiocar...

Patients with non-osseointegrated implants [+2]

Status: Recruiting

Characterizing the Inflammation Around Dental Implants: Bacterial Infection, Hypersensitivity or Both?

The use of titanium dental implants has become a common modern treatment to restore teeth. Although the success rate of dental implants is high, inflammation around the dental implant still occurs. The current study will investigate if the inflammation around the implant is due to bacterial infection, hypersensitivity or both.

Participants needed: 40
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: McGill University Health Centre/Research Institute of the McGill University Health CentreUpdated: Jul 23, 2024Locations: 1
Eligibility criteria

Received at least one functional implant (implant restored with a prothesis); [+1]

Dental records with incomplete information; [+9]

Status: Recruiting

5-year Follow up Study on the Comparative Performance of Two-piece Zirconia and Titanium Implants

A post-market, randomized-controlled, superiority clinical study to compare medium-term performance and safety of the Straumann PURE 2-piece Ceramic Implant with Straumann Bone Level Implant using a fully digital workflow.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: The University of Hong KongUpdated: Nov 21, 2023Locations: 2
Eligibility criteria

Patients must have voluntarily signed the Informed Consent Form before any study... [+2]

Patients with conditions or circumstances, in the opinion of the Investigator, w... [+1]

Status: Recruiting

SINUS FLOOR WITH OSSEODENSIFICATION OR LATERAL WINDOW

This study will compare patient-reported outcomes, as well as the type and incidence of complications, and bone marginal loss after 12 months in implants installed using the transcrestal approach (tSFE) with an osseodensification system (performed according to the protocol by Huwais et al. 2018), or installed simultaneously using the lateral window technique (lSFE) with sinus lift. A blind, randomized, controlled clinical trial will be carried out with individuals over 18 years old, and with single tooth loss in the posterior maxilla, where the residual bone height (RBH) is 3 to 5 mm. The tSFE will be performed with osseodensification burs (Densa Bur, Versah, USA) using a counterclockwise motion, associated to synthetic biomaterial (hydroxyapatite and beta-tricalcium phosphate). The lSFE technique will require the sinus to be filled with the same biomaterial as the group using the other technique, and the antrostomy to be covered with a polydioxanone-based membrane. The patient's post-operatory perceptions will be evaluated by self-administered questionnaires quantifying social and professional isolation, physical appearance, duration and changes in quality of life, eating and speech, diet variations, and sleep deficiency for 2 weeks after the procedure. Pain will be assessed with the visual analogue scale (VAS). Immediately after prosthetic rehabilitation, cone beam tomography will be performed. Controls at 6 and 12 months will be performed. In these images, the marginal bone level in relation to a fixed reference point on the implants (upper part of the platform) will be measured mesially and distally in each implant, using a specific program (ImageJ - version 1.49v / NIH software - Bethesda, MD, USA). Generalized estimating equations will be used to compare the two treatments overtime. The significance level used will be 0.05.

Participants needed: 38
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Federal University of Rio Grande do SulUpdated: Nov 8, 2023Locations: 1
Eligibility criteria

Maxillary sinuses that have residual bone height between at least 3 mm and 5 mm; [+6]

- Those with sinus pathology; [+9]

Status: Recruiting

Immediate Versus Delayed Loading of Single Posterior Zirconia Implants

The main aim of the present study is to investigate implant success rate after 5 years of function of immediate (Test group; within 7 days of implant placement) versus delayed (Control group; 8 weeks after implant placement) loading of two-pieces zirconia implant, placed in pristine bone without bone regeneration. Implant success rate will be defined according to Buser's criteria. Secondary endpoints: Marginal bone level (MBL) evaluation by means of standardized radiographs; Clinical evaluation of biological (e.g. Plaque Index, PI; Probing Pocket Depth, PPD, Bleeding on Probing, BOP; suppuration upon probing/palpation) and prosthetic/technical complications; Clinical evaluation of soft tissue width, keratinized tissue, marginal and interproximal soft tissue recession; Patient reported outcome measures (PROMs) by questionnaire administration:

Participants needed: 220
Trial details
Phase: Phase 4Age: 18-80Biological sex: AllType: InterventionalSponsor: University of MilanUpdated: May 1, 2023Locations: 1
Eligibility criteria

Sistemically healthy patients [+7]

Heavy smokers (>10 cigarettes a day) [+11]