Impact of Isoflurane and Sevoflurane on Oxidative Stress in Patients Undergoing Laparoscopic Cholecystectomy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-60
SponsorAin Shams University
About this trial
The primary aim of this work is to assess the impact of exposure to isoflurane or sevoflurane as an inhalation anesthetic on the oxidative stress and inflammatory conditions in patients undergoing elective moderate invasive surgery (laparoscopic cholecystectomy).
Eligibility criteria
Qualifiers
Age from 20 to 60 years.
Both sexes.
American Society of Anesthesiologists (ASA) Physical Status I-II.
Undergoing elective laparoscopic cholecystectomy under general anesthesia.
Disqualifiers
Refusal of participation in the study by patients.
Diabetes (type I or II), endocrine system, and immune system diseases.
Chronic infection and sepsis.
Cardiac condition as classified bythe New York Heart Association (NYHA) > class II.
Trial design
Treatments tested in this trial
- Isoflurane
- Sevoflurane
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov