Surgery is the front-line therapy for non-small cell lung cancer (NSCLC) but postoperative complications remains high and patients' long-term outcome is still challenging. In addition to surgery, anesthetic management particularly intraoperative blood pressure management and use of dexamethasone may affect patients' early and long-term outcomes after surgery for NSCLC. This study aims to investigate the impact of intraoperative blood pressure management and dexamethasone administration on early and long-term outcomes in patients undergoing surgery for lung cancer.
Aged >50 years but <90 years.
Diagnosed as resectable primary non-small cell lung cancer (stage IA-IIIA) and scheduled for radical surgery with an expected duration of >2 hours.
Agree to participate in this study and sign the informed consent.
Clinical examinations suggest non-resectable lung cancer or patients scheduled for a biopsy surgery.
Recurrent or metastatic lung cancer.
History of cancer or complicated with cancer in other organs.
Long-term exposure to glucocorticoids or other immunosuppressant(s) due to autoimmune disease or organ transplantation.