Investigation of the Relationship Between Periodontitis and Sleep Quality

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorUskudar University

About this trial

This project aims to investigate the relationship between periodontitis and sleep quality. Its originality lies in evaluating the association between periodontal status and sleep quality together with salivary interleukin-6 (IL-6), interleukin-6 (IL-10) IL-10, and pentraxin-3 levels. In particular, examining the relationship of sleep quality with biological, psychological, and lifestyle factors through periodontitis and salivary IL-6, IL-10, and pentraxin-3 levels has not been previously studied in the literature. Methodologically, periodontal status will be determined through clinical examination; participants' Pittsburgh Sleep Quality Index and Multidimensional Fatigue Inventory scores will be recorded; and salivary IL-6, IL-10, and pentraxin-3 levels will be measured. The obtained data will be compared using statistical analyses to determine the strength of the relationship between periodontitis severity and sleep quality. From a management perspective, the project will be conducted following approval from the ethics committee. In terms of broader impact, the results are expected to scientifically demonstrate the relationship between periodontitis and sleep quality, contribute to the adoption of a holistic health approach in clinical practice, and increase public health awareness. Additionally, the project is expected to provide a foundation for future research on the relationship between oral health and quality of life.

Eligibility criteria

Qualifiers

systemically healthy,

clinical diagnosis of periodontitis,

clinical diagnosis of periodontal health

Disqualifiers

history of regular use of systemic antibiotics, anti-inflammatory, or antioxidant drugs (previous 6 months);

nonsurgical periodontal treatment (previous 6 months);

surgical periodontal treatment (previous 12 months);

presence of <20 teeth;

Trial design

Treatments tested in this trial

  • Periodontal examinations
  • Collection of saliva samples
  • Pittsburgh Sleep Quality Index
  • (Multidimensional Assessment of Fatigue

Treatment groups

48 Participants
are divided into 2 treatment groups

Sponsors and collaborators