This study investigates whether taking the amino acid L-serine, either alone or in combination with targeted strength training, can have a positive effect on mental performance, brain function, and physical fitness in older people.
Healthy, independent women and men aged 65 to 85 are eligible to participate. Participants will be randomly assigned to one of three groups: placebo, L-serine, or L-serine combined with strength training.
Cognitive tests, physical performance tests, and blood and brain tests will be conducted over a period of 48 weeks. The aim is to gain a better understanding of how nutrition and exercise can contribute to healthy aging.
Men and women between the ages of 65 and 85
Mini-Mental-State >23
Independently mobile, without aids (walker, cane, etc.)
Chronic diseases that contraindicate medical training therapy
Regular strength training (>1x/week) in the last 6 months before confinement
Frailty Index ≥ 3
Lack of written consent to test physical performance
University of Vienna
Lead sponsor
Medical University of Vienna
Collaborator