LiverPAL: A Trial of Inpatient Palliative Care for Patients With Advanced Liver Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMassachusetts General Hospital
About this trial
The goal of this clinical trial is to evaluate whether early integration of palliative care in the care of hospitalized patients with advanced liver disease (AdvLD) can improve patients' quality of life, physical symptoms, mood, and serious illness communication. Palliative care is a medical specialty focused on lessening (or "palliating") symptoms and assisting in coping with serious illness.
Eligibility criteria
Qualifiers
Ascites (requiring diuretics or serial large volume paracenteses)
Spontaneous bacterial peritonitis
Hepatic hydrothorax (requiring diuretics)
Variceal bleed (with one or more occurrences)
Disqualifiers
Prior history of liver transplantation
Have uncontrolled hepatic encephalopathy, cognitive impairment, psychiatric disorder or other comorbid condition which the primary medical, hepatology, and/or transplant surgery teams believes prohibits the ability to provide informed consent
Current or recent (within 5 years of receiving curative cancer treatment) history of extrahepatic malignancy (excluding non-melanoma skin cancer)
Presence of hepatocellular carcinoma beyond Milan criteria
Trial design
Treatments tested in this trial
- LiverPAL
Treatment groups
200 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov