Liver Disease Chronic

5

Review clinical trials related to Liver Disease Chronic. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluation of the Hepatoprotective Effects of a Nutritional Supplement in Patients With Liver Disease Secondary to Chronic Hepatitis C Virus Infection (RESQUETI Study).

The purpose of this clinical trial is to evaluate whether a nutritional supplement containing resveratrol, quercetin, taurine, inulin, and whey protein improves biochemical and molecular markers, as well as clinical outcomes, in patients with liver disease related to chronic hepatitis C infection. The study will compare the investigational supplement with an active control (whey protein alone) to determine whether the combination formulation provides additional benefits on liver-related biomarkers and clinical assessment. Participants will: Take the investigational supplement or active control daily for 12 weeks. Attend clinic visits every 4 weeks for laboratory testing and clinical evaluations.

Participants needed: 26
Trial details
Age: 18-69Biological sex: AllType: InterventionalSponsor: University of GuadalajaraUpdated: Mar 23, 2026Locations: 2
Eligibility criteria

Patients with alcohol consumption within the past 6 months. Patients with a hist...

Status: Not yet recruiting

Validation of Different Methods for HepQuant DuO® Blood Sample Collection

This is a study to see the agreement of blood samples collected through different means and tube types for the HepQuant DuO Test. The HepQuant DuO Test is a blood-based test that involves a drink of a natural compound, cholate, and blood samples at 20 and 60 minutes. The study team is collecting clinical and laboratory data from patients living with chronic liver disease and healthy adult volunteers. The study has up to 2 study visits at an outpatient clinic and can take up to 4 weeks for a participant to complete study. At these visits, participants will undergo a HepQuant DuO test and other standard lab tests. In addition, the study team will ask about a participant's experience with different blood sampling methods.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: HepQuant, LLCUpdated: Mar 16, 2026
Eligibility criteria

adult healthy participant with no major comorbidities and lean body mass (BMI 18... [+1]

under the age of 18 [+4]

Status: Recruiting

HepHospital: A Pilot Trial of a Hepatology Home Hospital Intervention for Patients With Advanced Liver Disease

This research study is evaluating a program that entails a healthcare at home intervention for people with advanced liver disease.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Massachusetts General HospitalUpdated: Jul 24, 2025Locations: 2
Eligibility criteria

Adult patients ≥ 18 years old with diagnosis of cirrhosis based on histology, ra... [+3]

History of solid organ transplantation [+6]

Status: Recruiting

LiverPAL: A Trial of Inpatient Palliative Care for Patients With Advanced Liver Disease

The goal of this clinical trial is to evaluate whether early integration of palliative care in the care of hospitalized patients with advanced liver disease (AdvLD) can improve patients' quality of life, physical symptoms, mood, and serious illness communication. Palliative care is a medical specialty focused on lessening (or "palliating") symptoms and assisting in coping with serious illness.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Massachusetts General HospitalUpdated: Jul 17, 2025Locations: 1
Eligibility criteria

Ascites (requiring diuretics or serial large volume paracenteses) [+5]

Prior history of liver transplantation [+8]

Status: Not yet recruiting

Albumin Catabolic Rate Measured by a Stable Isotope

The goal of this physiological study is to compare albumin catabolic rate measured by a stable isotope labeled amino acid in healthy volunteers and in patients with liver disease. At steady state synthesis and catabolism or degradation are equal. The primary questions it aims to answer are: * Is albumin catabolic rate lower in patients with liver disease? * Is albumin catabolic rate measured by stable isotopes in volunteers like historical controls measured by radio-iodinated albumin at the investigator's laboratory or elsewhere? Subjects will be given an oral dose of the deuterium labeled amino acid phenylalanine that will be incorporated by the liver in newly synthetized albumin molecules, and blood samples will be taken over 12 weeks to determine the catabolic rate of albumin.

Participants needed: 24
Trial details
Age: 40+Biological sex: AllType: InterventionalSponsor: Ake NorbergUpdated: Jul 25, 2023Locations: 1
Eligibility criteria

males and females >= 40 years (to be more like the anticipated age of the liver... [+4]

Planned surgical procedure within 3 months (due to possible blood loss i.e. loss... [+4]