Mechanisms of Visual Restoration After Occipital Stroke

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age21-80
SponsorUniversity of Rochester

About this trial

This project will collect brain imaging data to quantify the effects of early visual cortex damage and visual training interventions on the structure and function of the residual visual system. Our goal is to improve understanding of the consequences of permanent visual cortex damage in humans, and to understand how visual training impacts the function of the residual visual system to restore perception.

Eligibility criteria

Qualifiers

Subjects between 21 and 80 years of age

Subjects must be residents of the United States or Canada

Subjects must exhibit unilateral stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 80 years (verified by MRI and/or CT scans)

Subjects with reliable visual field defects in both eyes (homonymous defects) as measured by Humphrey, MAIA, Goldmann, and/or equivalent perimetry. This deficit must be large enough to enclose a 5-deg diameter visual stimulus.

Disqualifiers

None

Trial design

Treatments tested in this trial

  • MRI

Treatment groups

100 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Rochester

Lead sponsor

National Institutes of Health (NIH)

Collaborator

Research to Prevent Blindness

Collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborator

National Institute of Mental Health (NIMH)

Collaborator

University of Texas at Austin

Collaborator