About this trial
This project will collect brain imaging data to quantify the effects of early visual cortex damage and visual training interventions on the structure and function of the residual visual system. Our goal is to improve understanding of the consequences of permanent visual cortex damage in humans, and to understand how visual training impacts the function of the residual visual system to restore perception.
Eligibility criteria
Qualifiers
Subjects between 21 and 80 years of age
Subjects must be residents of the United States or Canada
Subjects must exhibit unilateral stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 80 years (verified by MRI and/or CT scans)
Subjects with reliable visual field defects in both eyes (homonymous defects) as measured by Humphrey, MAIA, Goldmann, and/or equivalent perimetry. This deficit must be large enough to enclose a 5-deg diameter visual stimulus.
Disqualifiers
None
Trial design
Treatments tested in this trial
- MRI
Treatment groups
Sponsors and collaborators
University of Rochester
Lead sponsor
National Institutes of Health (NIH)
Collaborator
Research to Prevent Blindness
Collaborator
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborator
National Institute of Mental Health (NIMH)
Collaborator
University of Texas at Austin
Collaborator