Hemianopia

9

Review clinical trials related to Hemianopia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Visual Restoration Using Focused Ultrasound Stimulation and Immersive Virtual Reality After Stroke

This research will explore if brain stimulation combined with virtual reality therapy improves visual impairment. The stimulation technique is called low-intensity focused ultrasound stimulation (LIFUS). The treatment uses ultrasound to stimulate vision specific parts of the brain. Before this therapy, the participants will get structural brain imaging. Functional brain imaging will be performed before and after the study's completion to measure brain activity response to therapy. The purpose of this research study is to evaluate patients who have had a stroke between 6 and 24 months ago with a visual field impairment. The duration of active participation in the study is 1.5 months.

Participants needed: 28
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Duke UniversityUpdated: May 22, 2026Locations: 1
Eligibility criteria

≥ 18 years old of any gender and race [+2]

Documented history of severe dementia with or without medication before stroke t... [+6]

Status: Recruiting

Vision Loss Impact on Navigation in Virtual Reality

The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving. Using a novel Virtual Reality (VR) program, the researchers will gather data on steering behavior in a variety of simulated naturalistic environments. Through the combined use of computer vision, deep learning, and gaze-contingent manipulations of the visual field, this work will test the central hypothesis that changes to visually guided steering behaviors in CB are a consequence of changes to the visual sampling and processing of task-related motion information (i.e., optic flow).

Participants needed: 40
Trial details
Age: 21-75Biological sex: AllType: InterventionalSponsor: University of RochesterUpdated: Jan 9, 2026Locations: 1
Eligibility criteria

Residents of the United States or Canada [+5]

Those who have never driven or earned a drivers' license [+22]

Status: Not yet recruiting

Screening and Rehabilitation of Visual Field Defects in Post-Stroke Patients

In this study, the investigators will use a wearable device capable of performing this bedside assessment to evaluate the incidence of visual field loss in post-stroke patients. Furthermore, for those with visual field loss, the investigators will investigate whether integrating multisensory audio-visual rehabilitation into the standard physical rehabilitation protocol can help improve visual field loss compared to standard rehabilitation alone.

Participants needed: 300
Trial details
Age: 18-99Biological sex: AllType: InterventionalSponsor: Fondazione David Chiossone - Impresa SocialeUpdated: Jan 5, 2026
Eligibility criteria

Patients aged 18 to 99 years with stroke (excluding isolated cerebellar, brainst... [+1]

Presence of cognitive impairment (with an MMSE score less than 24), which limits... [+5]

Status: Recruiting

Mechanisms of Visual Restoration After Occipital Stroke

This project will collect brain imaging data to quantify the effects of early visual cortex damage and visual training interventions on the structure and function of the residual visual system. Our goal is to improve understanding of the consequences of permanent visual cortex damage in humans, and to understand how visual training impacts the function of the residual visual system to restore perception.

Participants needed: 100
Trial details
Age: 21-80Biological sex: AllType: ObservationalSponsor: University of RochesterUpdated: Dec 4, 2025Locations: 1
Eligibility criteria

Subjects between 21 and 80 years of age [+23]

Status: Recruiting

New Non-invasive Modalities for Assessing Retinal Structure and Function

This study investigates a new technology to assess the structure and function inside the eye. Retinal imaging of subjects with inner and outer retinal defects to detect areas of abnormal structure and function compared to other visual function tests.

Participants needed: 500
Trial details
Age: 18-99Biological sex: AllType: InterventionalSponsor: Randy KardonUpdated: Nov 24, 2025Locations: 1
Eligibility criteria

Not listed

Status: Recruiting

Vision on the Road: Vision Rehabilitation for Driving After Stroke

The goal of this clinical trial is to learn if vision training works to improve functional vision in people with visual field loss after stroke. The investigators want to know more about how people perceive their own functional vision and ability to compensate for visual field loss in daily activities. The main questions the study aims to answer are: * Does vision training improve dimensions of functional vision? * How does vision training affect the participants's perception of functional vision and the ability to compensate for visual field loss? Researchers will compare the effect of home-based vision training to standard care (no vision training) on functional vision. Participants will: * Participate in home-based vision training or standard care for 8 weeks * Be contacted once a week by phone * Keep a training diary

Participants needed: 52
Trial details
Age: 20-85Biological sex: AllType: InterventionalSponsor: University of South-Eastern NorwayUpdated: Aug 29, 2025Locations: 2
Eligibility criteria

Adults aged 20-85 years with a visual field defect following stroke [+6]

Presence of strabismus and/or visual neglect [+2]

Status: Recruiting

Visual Plasticity Following Brain Lesions

The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Georgetown UniversityUpdated: Aug 5, 2025Locations: 1
Eligibility criteria

At least 18 years of age. [+3]

Severe CNS diseases or disorders unrelated to the focal lesion, which could inte... [+7]

Status: Recruiting

Effect of Visual Retraining After Stroke

This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual system, visual perception, spatial awareness, and brain function. The investigators will also assess the effect of intensive visual retraining on the residual visual system, processing of visual information and the use of such information in real-world situations following damage. This research is intended to improve our understanding of the consequences of permanent visual system damage in humans, of methods that can be used to reverse visual loss, and of brain mechanisms by which visual recovery is achieved.

Participants needed: 100
Trial details
Age: 21-80Biological sex: AllType: InterventionalSponsor: University of RochesterUpdated: Jul 16, 2025Locations: 1
Eligibility criteria

Between 21 and 80 years of age [+26]

Status: Recruiting

Biofeedback Training for Hemianopia

This is a prospective study that compares biofeedback training on the microperimetry (BT) to a control group in patient s with hemianopia. The patients receive 5 sessions of 20 minutes to stimulate with light and sound the brain in using the best residual area on the visual fields post-brain injury visual loss. Visual tests and quality of life questionnaire are performed pre-and-post-training.

Participants needed: 70
Trial details
Age: 18-90Biological sex: AllType: InterventionalSponsor: University Health Network, TorontoUpdated: May 29, 2025Locations: 1
Eligibility criteria

Not listed