Mechanisms of Written Exposure Therapy in Residential SUD Treatment
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorMclean Hospital
About this trial
The goal of this clinical trial is to learn how Written Exposure Therapy (WET), a brief treatment for PTSD, works among individuals with substance use disorders (SUD) engaged in residential SUD treatment and how biology may influence treatment. The main questions it aims to answer are:
* Does WET improve PTSD and substance use outcomes among individuals with SUD+PTSD? * Does WET improve physiological responses and craving to trauma cues? * Do sex hormones influence changes physiological responses and craving during treatment among women?
Participants will:
* Complete WET or a neutral writing in addition to their residential SUD treatment * Complete two laboratory sessions before and after treatment * Complete follow-up surveys and interviews at 1- and 3-months post-treatment
Eligibility criteria
Qualifiers
ability to understand and sign informed consent
ability to write in English;
age between 18-55 (average age of menopause in the US)
[women only] naturally cycling (i.e., regular cycles, not on gonadal-related hormones)
Disqualifiers
presence of a psychiatric or medical condition that would interfere with participation (e.g., severe, uncontrolled psychosis)
prescription of a PRN benzodiazepine
current PTSD treatment
Trial design
Treatments tested in this trial
- Written Exposure Therapy
- Neutral Writing
Treatment groups
108 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov