About this trial
The investigators aim to validate markers of metabolic fluid-responsiveness in children with acute circulatory failure following cardiac surgery. This would allow physicians to identify which patient could benefit the most from fluid expansion, thus avoiding useless and potentially dangerous fluid expansions that could lead to fluid overload. To this end, The investigators will evaluate the diagnostic accuracy of the ratio of central venous to arterial carbon dioxide tension (Pv-aCO2) to arteriovenous oxygen content (CavO2), a simple biological marker of anaerobic metabolism, for the diagnosis of metabolic fluid responsiveness defined as a significant increase in oxygen consumption (VO2) after fluid expansion.
Eligibility criteria
Qualifiers
Age less than or equal to 15 years old
Hospitalization in a pediatric intensive care unit after cardiac surgery
Prescription by the attending physician of a fluid expansion of 10ml/kg
Prescription of arterial and venous blood gas before and after the volume expansion to help manage acute circulatory failure
Disqualifiers
Patient less than 37 weeks' corrected gestational age
Hemodynamic instability making the delay necessary for any test dangerous
Supine position contraindicated or deleterious
Impairment of echocardiographic acoustic window or restless patient making ultrasonography impossible
Trial design
Treatments tested in this trial
- Not listed