Circulatory Failure / Shock State

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Review clinical trials related to Circulatory Failure / Shock State. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Metabolic Fluid Responsiveness in Children

The investigators aim to validate markers of metabolic fluid-responsiveness in children with acute circulatory failure following cardiac surgery. This would allow physicians to identify which patient could benefit the most from fluid expansion, thus avoiding useless and potentially dangerous fluid expansions that could lead to fluid overload. To this end, The investigators will evaluate the diagnostic accuracy of the ratio of central venous to arterial carbon dioxide tension (Pv-aCO2) to arteriovenous oxygen content (CavO2), a simple biological marker of anaerobic metabolism, for the diagnosis of metabolic fluid responsiveness defined as a significant increase in oxygen consumption (VO2) after fluid expansion.

Participants needed: 110
Trial details
Age: 0-15Biological sex: AllType: ObservationalSponsor: University Hospital, BordeauxUpdated: Dec 1, 2025Locations: 8Duration: 28 Days
Eligibility criteria

Age less than or equal to 15 years old [+5]

Patient less than 37 weeks' corrected gestational age [+4]