Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-48
SponsorBagcilar Training and Research Hospital

About this trial

Study Description (For Patients, Families, and Healthcare Providers)

Purpose:

The aim of this study is to evaluate the effectiveness and safety of methotrexate treatment in women with ectopic pregnancy who belong to a group for whom this treatment is relatively contraindicated.

Background:

Methotrexate is a medication commonly used in the treatment of ectopic pregnancy (a pregnancy that occurs outside the uterus, usually in the fallopian tube). However, in certain conditions - such as kidney or liver dysfunction - methotrexate use may carry increased risks. These situations are known as relative contraindications. This study will retrospectively examine treatment outcomes in this specific patient population.

Method:

The study will analyze medical records of patients who were previously treated with methotrexate for ectopic pregnancy. No new interventions will be performed. The analysis will be based solely on existing clinical data.

Why Is This Important? The findings of this study may help us better understand the safety limits of methotrexate therapy and guide healthcare providers in managing similar cases in the future.

Eligibility criteria

Qualifiers

Diagnosed with ectopic pregnancy

Received methotrexate (MTX) treatment

Underwent surgical treatment due to lack of response to MTX therapy

Compliant with treatment follow-up

Disqualifiers

Participants with contraindications to methotrexate (MTX) treatment

Participants non-compliant with follow-up

Trial design

Treatments tested in this trial

  • Drug: Methotrexate (MTX) Patients received methotrexate treatment according to institutional protocols. Dosage and administration routes were recorded retrospectively. For patients who did not respond

Treatment groups

230 Participants
are divided into 1 treatment group