The aim of the study is to compare the effects of conventional Ultra High Temperature (UHT) milk containing both A1 and A2 type β-caseins (CON) with a2 UHT Milk containing A2 type β-casein only (A1PF) on inflammation, tolerance, and GI symptoms in pregnant women as well as infants' birth outcomes from 12 weeks' gestation up to 40 days post-birth.
20-35 years of age
Recruited at <12 weeks of gestation
Intention to deliver at study site hospital
Singleton pregnancy
Body mass index ≥ 35 at enrolment
Cow's milk intolerance or allergy
Significant systemic disorder (e.g., cardiac, respiratory, endocrinological, hemato-logic, or GI); pre-pregnancy diabetes, hypertension, or other medical conditions that preclude participation per the investigator's judgement
Taking any prescribed chronic medications
a2 Milk Company Ltd.
Lead sponsor
Edanz Inc
Collaborator
Cyanth (Wuxi) Health Technology Co. Ltd.
Collaborator
Affilicated Hospital of Jiangnan University
Collaborator
Guangzhou Trials Medical
Collaborator