About this trial
The primary objective for this project is to test whether affective executive functioning is a mechanism of action of mindfulness-based cognitive therapy and Wellness for Wellbeing. The main questions it aims to answer are:
1. Test the effect of MBCT vs. Wellness for Wellbeing on affective inhibition (i.e., emotionally valenced inhibition as measured via the affective Go/No Go task) using an RCT. 2. Test the effect of MBCT vs. Wellness for Wellbeing on (a) affective updating and (b) affective shifting. Outcomes will be measured with the affective n-Back and the affective Internal Switching Task, respectively.
3a) The investigators will examine whether depression symptom severity co-varies with change in affective executive functioning (i.e., affecting inhibition, shifting, and updating) over time. 3b) The investigators will examine whether compliance with treatment protocol (e.g., number of classes attended, amount of home practice) predicts endpoint executive functioning.
Participants will complete surveys, interviews, and computer tasks, and will be randomized to either Mindfulness-Based Cognitive Therapy or Wellness for Wellbeing.
Eligibility criteria
Qualifiers
Adults 18 years or older
English fluency in order to complete study procedures
Normal vision or corrected to normal vision
QIDS score ≥ 5 and ≤ 15 to include individuals with elevated, but not severe symptoms of depression
Disqualifiers
None
Trial design
Treatments tested in this trial
- Mindfulness-Based Cognitive Therapy
- Wellness for Wellbeing
Treatment groups
Sponsors and collaborators
Butler Hospital
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
Collaborator