Depression in Remission

2

Review clinical trials related to Depression in Remission. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Mechanisms of Change of Positive Interventions in Reducing Vulnerability for Depression

The purpose of this study is to understand the effects of mindfulness and fantasizing in reducing perseverative cognition underlying vulnerability for depression.

Participants needed: 100
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: University Medical Center GroningenUpdated: Jun 16, 2026Locations: 1
Eligibility criteria

Participants should be between 18 and 60 years old. Participants should not exce... [+3]

Fulfilling criteria for any current DSM-5 diagnosis as objectified with the Stru... [+5]

Status: Recruiting

Mood and Thought Process Study

The primary objective for this project is to test whether affective executive functioning is a mechanism of action of mindfulness-based cognitive therapy and Wellness for Wellbeing. The main questions it aims to answer are: 1. Test the effect of MBCT vs. Wellness for Wellbeing on affective inhibition (i.e., emotionally valenced inhibition as measured via the affective Go/No Go task) using an RCT. 2. Test the effect of MBCT vs. Wellness for Wellbeing on (a) affective updating and (b) affective shifting. Outcomes will be measured with the affective n-Back and the affective Internal Switching Task, respectively. 3a) The investigators will examine whether depression symptom severity co-varies with change in affective executive functioning (i.e., affecting inhibition, shifting, and updating) over time. 3b) The investigators will examine whether compliance with treatment protocol (e.g., number of classes attended, amount of home practice) predicts endpoint executive functioning. Participants will complete surveys, interviews, and computer tasks, and will be randomized to either Mindfulness-Based Cognitive Therapy or Wellness for Wellbeing.

Participants needed: 76
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Butler HospitalUpdated: Nov 5, 2025Locations: 1
Eligibility criteria

Adults 18 years or older [+12]