Multicomponent Prehabilitation and Outcomes in Elderly Patients With Frailty

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65-89
SponsorPeking University First Hospital

About this trial

The study is designed to investigate the effect of a multicomponent prehabilitation pathway on early and long-term outcomes in elderly patients with frailty recovering from surgery for digestive cancer.

Eligibility criteria

Qualifiers

Age ≥65 years but <90 years;

Scheduled to undergo major surgery for digestive cancer with an expected duration of 2 hours and longer, including cancers of esophagus, stomach, small intestine, colon, rectum, pancreas, liver, and biliary tract;

Clinical Frailty Scale ≥5;

Provide written informed consent.

Disqualifiers

Preoperative history of schizophrenia, epilepsy, Parkinsonism, or myasthenia gravis;

Inability to communicate due to coma, profound dementia, or language barrier;

Inability to participate in preoperative rehabilitation due to paralysis, fracture or other movement disorder;

Inability to take oral diet due to preoperative gastrointestinal disease or other disease;

Trial design

Treatments tested in this trial

  • Preoperative nutritional optimization
  • Preoperative exercise training
  • Postoperative exercise training

Treatment groups

540 Participants
are divided into 2 treatment groups