About this trial
The study is designed to investigate the effect of a multicomponent prehabilitation pathway on early and long-term outcomes in elderly patients with frailty recovering from surgery for digestive cancer.
Eligibility criteria
Qualifiers
Age ≥65 years but <90 years;
Scheduled to undergo major surgery for digestive cancer with an expected duration of 2 hours and longer, including cancers of esophagus, stomach, small intestine, colon, rectum, pancreas, liver, and biliary tract;
Clinical Frailty Scale ≥5;
Provide written informed consent.
Disqualifiers
Preoperative history of schizophrenia, epilepsy, Parkinsonism, or myasthenia gravis;
Inability to communicate due to coma, profound dementia, or language barrier;
Inability to participate in preoperative rehabilitation due to paralysis, fracture or other movement disorder;
Inability to take oral diet due to preoperative gastrointestinal disease or other disease;
Trial design
Treatments tested in this trial
- Preoperative nutritional optimization
- Preoperative exercise training
- Postoperative exercise training