Old Age; Debility

9

Review clinical trials related to Old Age; Debility. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Combined Effects of NMES and LIRT on Muscle Strength, Girth, and Physical Endurance in the Geriatric Population

This study will employ a randomized controlled trial design with a pre-post design to investigate the combined effects of Neuromuscular Electrical Stimulation (NMES) and Low-Intensity Resistance Training (LIRT) on muscle strength, muscle girth, and physical endurance in the geriatric population. Participants will be randomly assigned to either an intervention group or a control group.

Participants needed: 44
Trial details
Age: 65-85Biological sex: AllType: InterventionalSponsor: Riphah International UniversityUpdated: Jun 12, 2026Locations: 1
Eligibility criteria

Both male and female will be added(29) [+4]

Participants with a MoCA score of less than 26 will be excluded to ensure adequa... [+2]

Status: Recruiting

Impact of a Physical Exercise Program in a Rural Area

With this work we want to assess whether there are differences in the amount of physical activity per week, measured by accelerometry in 3 groups of subjects, where one group (G1) has been carrying out a PA program called "Enguera Sé Saludable" for a year. another group (G2) newly introduced to the same exercise program, and a control group (G3) that does not carry out an exercise program but declared itself active.

Participants needed: 140
Trial details
Age: 59+Biological sex: AllType: InterventionalSponsor: University of ValenciaUpdated: Apr 28, 2026Locations: 1
Eligibility criteria

Adults over 59 years of age. [+3]

Patients who do not wear the accelerometer 600 minutes a day for at least 3 days... [+2]

Status: Recruiting

Relationship Between Neuropathic Pain and Geriatric Assessment Parameters in Patients Aged 80 Years and Older

This study aimed to determine the frequency of neuropathic pain in individuals aged 80 years and older and to evaluate the relationship between neuropathic pain and comprehensive geriatric assessment parameters.

Participants needed: 450
Trial details
Age: 80+Biological sex: AllType: ObservationalSponsor: Sultan 1. Murat State HospitalUpdated: Mar 23, 2026Locations: 1
Eligibility criteria

Age 80 years or older [+2]

Patients with dementia classified as CDR-2 or CDR-3 according to the Clinical De... [+4]

Status: Not yet recruiting

Efficacy of Subclavian Vein/Artery Diameter Index in Predicting the Incidence of the Spinal-Induced Hypotension in Geriatric Patients

The hypothesis of the study will be that the subclavian vein/subclavian artery diameter (SCVD/SCAD) index will be a good predictor of spinal-induced hypotension in geriatric patients.

Participants needed: 107
Trial details
Age: 65+Biological sex: AllType: ObservationalSponsor: Tanta UniversityUpdated: Dec 16, 2025Locations: 1
Eligibility criteria

1. Patients aged 65 or older. 2. Lower body surgeries to be done with spinal ane...

Status: Recruiting

Multicomponent Prehabilitation and Outcomes in Elderly Patients With Frailty

The study is designed to investigate the effect of a multicomponent prehabilitation pathway on early and long-term outcomes in elderly patients with frailty recovering from surgery for digestive cancer.

Participants needed: 540
Trial details
Age: 65-89Biological sex: AllType: InterventionalSponsor: Peking University First HospitalUpdated: Jul 31, 2025Locations: 1
Eligibility criteria

Age ≥65 years but <90 years; [+3]

Preoperative history of schizophrenia, epilepsy, Parkinsonism, or myasthenia gra... [+5]

Status: Recruiting

Dual Task Perturbation Training for OAwMCI

Studies have determined that compared to cognitively intact older adults (CIOA), older adults with mild cognitive impairment (OAwMCI) exhibit more pronounced balance and gait impairments which lead to an increased risk of falls and mobility decline. Such impairments are evident during dual-tasking (i.e., simultaneous performance of cognitive and motor task) and OAwMCI have demonstrated an increased cognitive-motor interference (deteriorated performance of either or both cognitive/motor task). Furthermore, our preliminary laboratory findings indicate that compared to CIOA, OAwMCI in response to large-magnitude treadmill perturbations exhibits poor reactive responses (first line of defense against balance loss) and are unable to modulate their responses as the magnitude of perturbation increases. Despite that conventional exercise methods offer beneficial effects; they comprise of self-initiated task-specific exercises and may not focus on training reactive responses. Additionally, due to the presence of subtle balance and gait deficits, clinical measures used may not be sensitive enough to determine the risk of fall post-training. Furthermore, these training methods incorporate multiple sessions due to which adherence to exercise training is difficult with only a fraction of the older adults benefiting from it. Therefore, it is essential to incorporate a task-specific strategy that promotes factors associated with falling like balance control, muscular responses, coordination of limbs, and cognition through which OAwMCI may acquire maximum benefits to prevent a balance loss. One feasible method, which harnesses technology that can be used to deliver balance disturbances either while standing or walking in a consistent and controlled manner, is via a custom-based motorized treadmill. The scientific rigor from preliminary studies has reported a successful reduction of falls through a single session exposing CIOA to multiple treadmill-induced perturbations during gait and has shown significant improvement in reactive responses. For that reason, this stage 1 pilot study will examine the feasibility, applicability, and tolerability of a combined cognitive, and perturbation training on biomechanical determinants associated with falls and promote physical activity: kinematic variables, muscular responses, and cognitive function.

Participants needed: 142
Trial details
Age: 55+Biological sex: AllType: InterventionalSponsor: University of Illinois at ChicagoUpdated: Nov 26, 2024Locations: 1
Eligibility criteria

Age group: Older adults between the age group > 55 years old with MOCA less than... [+5]

Participants will not proceed with the study if any of the following occurs at b... [+3]

Status: Recruiting

Significant Activities in the Integrated Person-centered Care Model

The increasing life expectancy and global aging population necessitate changes in long-term gerontological services based on Person-Centred Care approaches. This study aims to improve Person-Centred Care in geriatric centers through meaningful activities and the role of occupational therapists and direct care professionals in developing these activities. A descriptive cross-sectional quasi-experimental design was proposed, with 10 participants.

Participants needed: 10
Trial details
Age: 60+Biological sex: MaleType: InterventionalSponsor: Universidad de BurgosUpdated: Oct 2, 2024Locations: 1
Eligibility criteria

That the direct care worker has a degree as a nursing assistant, dependency care... [+3]

Workers who work night shift only. [+2]

Status: Not yet recruiting

Brain Gym Therapy on Quality of Sleep Among Elderly People

This clinical trial aims to evaluate the impact of Brain Gym Therapy on the quality of sleep among elderly individuals attending healthcare facilities. The study will explore whether this non-pharmacological intervention can improve sleep quality, which is often compromised in the elderly population due to various health conditions and age-related changes. Participants will undergo Brain Gym Therapy sessions over a specified period, and their sleep quality will be assessed using validated sleep measurement tools. The findings may provide insights into alternative methods for enhancing sleep in older adults.

Participants needed: 120
Trial details
Age: 60+Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Aug 14, 2024
Eligibility criteria

Not listed

Status: Recruiting

The Effect of Home Visit Supported Nursing Education Program on Some Parameters in Elderly People Living Alone at Home

It is aimed to develop healthy lifestyle behaviors of elderly people living alone at home, reduce their loneliness levels and increase their social support capacity.The research was planned as a quasi-experimental research. The research population consists of elderly people living alone at home who are registered to the Elderly and Home Care Unit of a Municipality of a province.

Participants needed: 48
Trial details
Age: 65-95Biological sex: AllType: InterventionalSponsor: Kastamonu UniversityUpdated: Jul 24, 2024Locations: 2
Eligibility criteria

Being 65 years or older [+3]

Individuals under the age of 65 [+2]