Neuroimaging of Adolescent Cannabis Use Treatment

ConditionsCannabis Use Cannabis Dependence Cannabis Use Disorder Cannabis Abuse Cannabis Intoxication Cannabis Smoking Cannabis Withdrawal Cannabis-Related Disorder Cannabis Abuse, in Remission Cannabis Abuse, Episodic Use Marijuana Marijuana Abuse Marijuana Use Marijuana Smoking Marijuana Dependence Marijuana User Marijuana-Related Disorder Marijuana Use Disorder Addiction Addiction, Substance Substance Use Substance Use Disorders Substance Dependence Substance Abuse Substance Related Problem Substance Abuse Drug Chronic

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age14-17

SponsorIndiana University

About this trial

This study is testing whether brain activity related to learning can help predict how well teens respond to a treatment program designed to reduce cannabis use. Teens ages 14-17 will complete a brain scan and then take part in 10 weekly virtual sessions where they report cannabis use and complete drug tests at home. Participants can earn prizes for staying cannabis-free.

Eligibility criteria

Qualifiers

14-17 year old youth

Guardian 18 years or older

Youth is MRI-eligible: No metal implants, prosthetics, orthodontic devices, transdermal medication patches, piercings and/or hair or eyelash extensions that cannot easily be removed, metallic ink tattoos on the neck or face, or claustrophobia, and are not pregnant

Youth must endorse having used cannabis at least once per week over the past month OR youth must have been diagnosed with cannabis use disorder within the past three months

Disqualifiers

Youth has a history of Fetal Alcohol Spectrum Disorder, intellectual disorders, pervasive development disorder or autism spectrum disorder, psychotic disorders, history of neurological problems (epilepsy, traumatic brain injury, brain tumor, cerebrovascular disease) by parent/guardian report

Youth or caretaker who is monolingual non-English speaker

Youth who is currently experiencing active psychosis symptoms or suicidal/homicidal ideation or who has been hospitalized within the past 6 months for psychosis or suicidality/homicidality

Youth who is currently undergoing contingency management treatment for cannabis use disorder

Trial design

Treatments tested in this trial

Contingency Management
Elastic Net Regression

Treatment groups

80 Participants

are divided into 1 treatment group

Sponsors and collaborators

Indiana University

Lead sponsor

National Institute on Drug Abuse (NIDA)

Collaborator

Source ClinicalTrials.gov