Omega-3 Fatty Acids and Subconcussive Head Impacts
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-30
SponsorIndiana University
About this trial
The purpose of the proposed double-blind, randomized placebo-controlled trial is to understand how supplementation with fish oil \[docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)\] promote brain health against soccer heading. The study involves taking DHA+EPA or placebo, questionnaires, blood draws, brain imaging, tests to evaluate heart function, and soccer headings.
Eligibility criteria
Qualifiers
Between age 18-30
Current or former soccer player
At least 5 years of soccer heading experience
Have internet access
Disqualifiers
Any head or neck injury within 6 months before the study
Implanted metal/magnetic devices (e.g., orthodontic braces
Diagnosed autonomic or cardiovascular diseases (e.g., hypertension)
Consuming oily fish (2 servings or more/month: salmon, bluefin, swordfish, anchovies)
Trial design
Treatments tested in this trial
- Omega-3 Fatty Acids (EPA plus DHA)
- Organic soybean oil
- Soccer Heading Model
Treatment groups
208 Participants
are divided into 2 treatment groupsSponsors and collaborators
Indiana University
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborator
Source ClinicalTrials.gov