Optic Nerve Head Evaluation Through Multimodal Blood Flow Analysis: a Prospective Observational, Multi-center Study

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age12+
SponsorBarboni

About this trial

OCT-A and eco-colordoppler are technologies which enable optic nerve head (ONH) blood perfusion detection. The aim of the study is to assess ONH vascular and structural components in optic neuropathies with and without ONH edema or pseudo-edema with OCT-A, and analyze ONH blood-flow with eco-colordoppler.

Eligibility criteria

Qualifiers

Participant (or parents/legal representative/tutor for minors) is willing and able to give informed consent for participation in the study

patients affected by acute ONH edema (NAION, papilledema, optic neuritis)

patients affected by acute pseudoedema (LHON)

patients affected by chronic pseudoedema (LHON, ODD)

Disqualifiers

any other ONH disease or neurological /retinal disease impairing the evaluation of the ONH;

evidence of media opacities affecting the quality of the vascular assessment;

patients affected Alzheimer/Parkinson disease will be considered separately

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

70 Participants
are grouped into 1 trial group

Locations

This trial has no locations

Sponsors and collaborators

Barboni

Lead sponsor

IRCCS San Raffaele

Sponsor institution

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Collaborator

ASST Fatebenefratelli Sacco

Collaborator