Neuro-Ophthalmology

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Review clinical trials related to Neuro-Ophthalmology. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Diagnostic Accuracy of Optimized Diffusion-Weighted Imaging for Detecting Anterior Ischemic Optic Neuropathy

The patient presents to the ophthalmological emergencies and / or to the internal medicine department. NOIA clinical discovery Patient referred in radiology for brain and visual MRI. The two sequences added by the research (8 minutes) will be added to that of the treatment.

Participants needed: 250
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Fondation Ophtalmologique Adolphe de RothschildUpdated: Jan 5, 2026Locations: 3
Eligibility criteria

Patient over 18 years old [+4]

Contraindication to MRI (electrical device, metallic foreign body, claustrophobi... [+2]

Status: Recruiting

Safety and Normative Data With Neos™

The goal of this clinical study is to collect standard data for the medical device neos™. neos™ is a system that shows images and measures the resulting eye movements and pupil size. Collecting standard data involves three steps. First it is checked if neos™ eye-tracking works well. Eye-tracking means recording where a person is looking. After that it is checked if participants look at the images shown in neos™ as planned. Finally the eye movements and the pupil size are measured. This is done in healthy volunteers including children and persons with eye and brain problems. Participants in the study will wear a virtual reality headset. The screens in the headset will show different images. Cameras in the headset will record eye movements and pupil size. This will take about 15 minutes. During these 15 minutes the investigator looks at the following behaviors of the participants eyes: * Where are the eyes looking * How do the pupils react to light and darkness * How do the eyes move * How much can the participant see from the corner of their eyes * How well are the eyes working together

Participants needed: 200
Trial details
Age: 3+Biological sex: AllType: ObservationalSponsor: machineMD AGUpdated: Dec 2, 2025Locations: 3Duration: 1 Day
Eligibility criteria

Age > 3 [+3]

Known ophthalmological, neurological or vestibular disease [+10]

Status: Not yet recruiting

Optic Nerve Head Evaluation Through Multimodal Blood Flow Analysis: a Prospective Observational, Multi-center Study

OCT-A and eco-colordoppler are technologies which enable optic nerve head (ONH) blood perfusion detection. The aim of the study is to assess ONH vascular and structural components in optic neuropathies with and without ONH edema or pseudo-edema with OCT-A, and analyze ONH blood-flow with eco-colordoppler.

Participants needed: 70
Trial details
Age: 12+Biological sex: AllType: ObservationalSponsor: BarboniUpdated: Jul 20, 2025
Eligibility criteria

Participant (or parents/legal representative/tutor for minors) is willing and ab... [+4]

any other ONH disease or neurological /retinal disease impairing the evaluation... [+2]