Optimizing Early Nutrition Management of Extremely and/or Very Preterm Infants
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeUp to 1
SponsorChildren's Hospital of Fudan University
About this trial
A clinical quality improvement bundle on early nutrition supplementation is developed to improving the clinical outcomes (including growth, organ function, and neurodevelopment outcomes) of extremely and/or very preterm infants. This bundle consists of three aspects: individualized and precise human milk feeding, early enteral zinc supplementation, and routine parenteral carnitine supplementation.
Eligibility criteria
Qualifiers
(1) Admitted to the Neonatal Department of Children's Hospital of Fudan University during the study period.
(2) Preterm infants with a gestational age < 32 weeks or a birth weight < 1500 g.
(3) Admitted to the study center within 24 hours after birth.
(4) Obtained informed consent from family members.
Disqualifiers
(1) Newborns with severe congenital diseases, severe congenital malformations, chromosomal abnormalities, or genetic metabolic diseases.
(2) Death or discharge within two weeks after birth.
(1) Admitted to the Neonatal Department of Children's Hospital of Fudan University from January 2025 to December 2025.
(2) Preterm infants with a gestational age < 32 weeks or a birth weight < 1500 g.
Trial design
Treatments tested in this trial
- A nutritional improving bundle for the intervention group
- Routine nutritional strategies for the control group
Treatment groups
200 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov