Quality Improvement

12

Review clinical trials related to Quality Improvement. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Enhancing Operational Efficiency in Eye Care Services

Pushpagiri Vitreo Retina Institute (PVRI) based in Secunderabad is a tertiary care eye hospital providing specialty eye care services since 2007. Over 15-20 preplanned surgical/clinical procedures are conducted for patients requiring care on a daily basis. They range from simple cataract surgeries or injections to detailed specialty surgeries including Vitreo-retina, glaucoma, pediatric eye care and muscular conditions of the eye. All procedures are elective procedures and are pre-planned. The current study aims to improve hospital efficiency and reduce the total appointment time for patients. The current study aims to reduce patient overall waiting time by 15-25% by introducing simple patient identification tools to help streamline all planned procedures.

Participants needed: 400
Trial details
Age: Up to 85Biological sex: AllType: InterventionalSponsor: Seva Canada SocietyUpdated: May 5, 2026Locations: 1
Eligibility criteria

All patients undergoing pre-planned elective procedures in the unit listed on ap... [+1]

Patients undergoing emergency procedures. [+2]

Status: Not yet recruiting

Optimizing Early Nutrition Management of Extremely and/or Very Preterm Infants

A clinical quality improvement bundle on early nutrition supplementation is developed to improving the clinical outcomes (including growth, organ function, and neurodevelopment outcomes) of extremely and/or very preterm infants. This bundle consists of three aspects: individualized and precise human milk feeding, early enteral zinc supplementation, and routine parenteral carnitine supplementation.

Participants needed: 200
Trial details
Age: Up to 1Biological sex: AllType: InterventionalSponsor: Children's Hospital of Fudan UniversityUpdated: Apr 20, 2026Locations: 1
Eligibility criteria

(1) Admitted to the Neonatal Department of Children's Hospital of Fudan Universi... [+3]

(1) Newborns with severe congenital diseases, severe congenital malformations, c... [+6]

Status: Recruiting

Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences

Hospitals ineffectively examine the safety of their processes by relying on voluntary incident reporting (VIR) by clinical staff who are overworked and afraid to report. VIR captures only 1-10% of events, excludes patients and families, and underdetects events in vulnerable groups like patients with language barriers. Patients and families are vigilant partners in care who are adept at identifying errors and AEs. Failing to actively include patients and families in safety reporting and instead relying on flawed VIR presents an important missed opportunity to improve safety. To improve hospital safety, there is a critical need to coproduce (create in partnership with families) effective systems to identify uncaptured errors. Without this information, hospitals are impeded in their ability to improve patient safety. In partnership with diverse families, nurses, physicians, and hospital leaders, investigators created a multicomponent communication intervention to engage families of hospitalized children in safety reporting. The intervention includes 3 elements: (1) a multilingual mobile (email, text, and QR-code) reporting tool prompting families to share concerns and suggestions about safety, (2) family/staff education, and (3) a process for sharing family reports with the unit and hospital so systemic issues can be addressed.

Participants needed: 656
Trial details
Biological sex: AllType: InterventionalSponsor: Boston Children's HospitalUpdated: Mar 24, 2026Locations: 1
Eligibility criteria

Patient/Family/Caregiver who has been hospitalized on the study unit during the... [+1]

Admitted awaiting inpatient psychiatric placement [+6]

Status: Not yet recruiting

British Columbia Prescriber Feedback Program - Antimicrobial Resistance

The goal of this study is to evaluate an educational intervention that aims to reduce the number of unnecessary antibiotics prescribed by family physicians and nurse practitioners in British Columbia, Canada. The intervention materials include a confidential personalized prescribing "portrait" and an evidence-based educational summary (therapeutics letter), accompanied by an introduction letter. The main research questions are: 1. Will the intervention lead to a reduction in the overall number of antibiotics prescriptions started? 2. Will the intervention lead to a reduction in the proportion of antibiotics prescribed that are likely unnecessary, especially prescriptions for upper respiratory tract infections, acute bronchitis, acute sinusitis? Researchers will conduct an intervention study with family physicians and nurse practitioners in British Columbia, Canada. Participant clinicians will be randomly assigned to one of two groups. The Early Group will consist of 80% of the participants and will receive the intervention (prescribing portrait, evidence summary, and introduction letter) at the start of the study. The Delayed Group will consist of 20% of participants and will receive the intervention about nine months later. This study design allows most practitioners to receive the intervention early while still allowing time to compare the two groups to assess the impact. To estimate the impact of the intervention, researchers will use administrative health data to compare the prescribing of the Early Group with prescribing of the Delayed Group.

Participants needed: 7,626
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of British ColumbiaUpdated: Feb 24, 2026Locations: 1
Eligibility criteria

A valid MSP billing number; [+2]

Previously opted out of the Therapeutics Initiative Portrait program [+4]

Status: Not yet recruiting

Enhancing Mental and Physical Health of Women Veterans 3.0

Women Veterans are the fastest growing segment of VA users, with most users in midlife. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that they will want and be able to use those services. Furthermore, few VA improvement efforts have focused on women Veterans' health and health care in midlife. The EMPOWER QUERI 3.0 Program is a cluster randomized type 3 hybrid implementation-effectiveness trial testing two strategies designed to support implementation and sustainment of evidence-based practices for women Veterans in at least 18 VA facilities from 4 regions.

Participants needed: 18
Trial details
Biological sex: AllType: InterventionalSponsor: VA Office of Research and DevelopmentUpdated: Jan 21, 2026Locations: 1
Eligibility criteria

This study is recruiting VA sites - not individual patients. [+1]

N/A

Status: Not yet recruiting

Impact Evaluation of the Therapeutic Initiative's Prescribing Portrait and Therapeutics Letter on Opioid Use by Dentists

The aim of this study is to estimate the impact of providing personalized prescribing data and educational materials on opioid prescribing to dentists in British Columbia, Canada. The main research questions are: 1. What is the impact of an intervention on the use of opioids for dental pain? The intervention includes a personalized prescribing report (a "Portrait"), brief educational summary, and patient education materials; and 2. Does the impact of the intervention increase when dentists are also invited to attend facilitated audit-and-feedback group sessions and to develop a practice improvement plan? Using administrative health data, the prescribing of those in different combinations of materials in the Early Group will be compared to those in the Delayed Group to estimate the impact of the materials on prescribing by the dentists.

Participants needed: 3,498
Trial details
Biological sex: AllType: InterventionalSponsor: University of British ColumbiaUpdated: Jan 8, 2026Locations: 1
Eligibility criteria

Registered with the British Columbia Medical Services Plan (MSP) as being in act... [+5]

Had a medication dispensed under Plan P in the 12 months prior to the opioid pre... [+1]

Status: Recruiting

Introduction of an Operating Room Black Box to Identify, Analyse and Prevent Errors in the Vascular Hybrid Room

The "OR Black box", an inclusive multiport data capturing system has been developed and successfully used for detailed analysis of laparoscopic surgical procedures. A pilot study has shown that this system can be successfully installed in the hybrid room at Ghent University Hospital and used for detailed analysis of intra-operative errors and radiation safety issues in endovascular procedures. Secondary analysis of pilot study data via direct video coding assessed the relationship between leadership style of the surgeon and team behavior and possible fluctuations during surgery. This novel approach allows a prospective objective assessment of human and environmental factors as well as measurement of errors, events and outcomes. In this study, the aim is to use the acquired knowledge to characterize a chain of events, identify high-risk interventions and identify areas for improvement, both on an organizational, team or individual level. Hypothesis: non-technical skills, environmental factors and teamwork in the hybrid room correlate with surgical technical performance and error rates. Furthermore, we hypothesize that incidents and adverse events can be tracked to a chain of errors that is influenced by technical and non-technical skills as well as environmental factors.

Participants needed: 400
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: University GhentUpdated: Dec 22, 2025Locations: 1
Eligibility criteria

Patients undergoing elective (planned more than 48 hours) endovascular procedure... [+2]

No consent of patient [+3]

Status: Recruiting

Multicenter Clinical Translational Study of "ICU-NO CRBSI" Based on Improvement Science

The goal of this type of study is to construct the continuous quality promotion project "ICU-NO CRBSI(Catheter-Related Bloodstream Infection , CRBSI)" based on improvement science, and to verify its effect in the prevention of central venous catheter-related bloodstream infection and continuous quality improvement in ICU ( Intensive Care Unit , ICU) through multi-center implementation and two rounds of improvement. The main question\[s\] it aims to answer are: What is the incidence of catheter-related bloodstream infection in the ICU of participating units? How compliant are health care providers in the ICU with evidence-based sensory control practices for the prevention of catheter-associated bloodstream infection? Participants will be provided with the hospital's routine CVC (Central Venous Catheter ,CVC) care practices and CVC quality improvement measures based on evidence-based guidelines What technical and cultural support is needed to implement quality and safety improvement measures?

Participants needed: 8,050
Trial details
Biological sex: AllType: InterventionalSponsor: Fudan UniversityUpdated: Nov 17, 2025Locations: 1
Eligibility criteria

ICU stay over 48 hours [+1]

Pregnant patients [+2]

Status: Recruiting

CHIPs-VTE Study in Hospitalized Patients to Prevent Hospital-Acquired Venous Thromboembolism

Although pharmacologic and mechanical methods to prevent VTE are safe, effective, cost-effective, and advocated by authoritative guidelines,many studies continue to demonstrate that these preventive methods are significantly underutilized, especially in China.A number of quality improvements (QI) program have been established in several countries or hospitals.However,no exit effective protocol has been demonstrated well enough or adequate to drive breakthrough levels of improvement. A reliable and practical QI that can support hospitals or physicians in China is warranted.To evaluate the multifaceted quality improvement intervention effect in clinical setting, we will conduct a cluster-randomized clinical trial among China PUlmonary Thromboembolism REgistry Study (CURES) group, aiming to test whether it's applicable to real-world practice in China. A multicenter, two-arms, open-label clinical trial has been designed to determine whether the system-wide multifaceted intervention could increase the rate of at-risk participants who received prophylaxis (RP) and decrease the incidence of any hospital-associated VTE in 90 days during and after hospital admission. .Selected hospital will be regarded as a cluster and randomized into interventional or control group.In interventional group, eligible hospitalized patients will receive a variety of the multifaceted quality improvement(QI) interventions since admitted in hospital.In control group, patients will receive no more than common recommended care or an existing policy.The primary outcomes are the proportion of appropriate prophylaxis in hospitalized patients and the incidence of HA-VTE in 90 days after hospital admission.

Participants needed: 5,800
Trial details
Age: 14+Biological sex: AllType: InterventionalSponsor: China-Japan Friendship HospitalUpdated: Sep 17, 2025Locations: 1
Eligibility criteria

Aged ≥14 years [+2]

Inability to be followed-up at until 3 months after randomization [+4]

Status: Recruiting

The Impact of Fasting Duration on Quality of Recovery After Cesarean Section

This study will evaluate the effect of fasting duration and elective c-section start time on the overall quality of recovery. Patients will be seen 24 hours after surgery to answer 11 questions on their overall recovery after surgery. Several factors will be tracked to determine their effect on recovery, with the primary variable of interesting

Participants needed: 100
Trial details
Biological sex: FemaleType: ObservationalSponsor: Jewish General HospitalUpdated: Sep 4, 2025Locations: 1
Eligibility criteria

Presenting for elective c-section under spinal anesthesia

Unable to communicate in French or English [+2]

Status: Recruiting

National Emergency Bariatric Surgery Audit

The goal of this observational study is to investigate the incidence, management, and outcomes of complications following bariatric surgery in patients in the United Kingdom. The main questions it aims to answer are: * What is the prevalence of unplanned interventions due to complications following bariatric surgery in the UK? * What are the current practices for managing these complications, and how do they impact patient outcomes? Participants will: Be identified from hospitals treating patients presenting with complications following bariatric surgery. Have their data collected regarding demographics, surgical history, complications, treatments, and outcomes. Researchers will compare different management strategies and their impact on patient outcomes, with the aim of identifying best practices to improve emergency bariatric care and factors leading to patients attending as an emergency.

Participants needed: 500
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Bedfordshire Hospitals NHS Foundation TrustUpdated: Dec 17, 2024Locations: 1
Eligibility criteria

Admissions from i) the emergency department, clinic, urgent care or primary care... [+1]

age <18 years old [+2]

Status: Recruiting

Study to Evaluate the Impact of the Recovery Pathway on Postoperative Leght of Stay in Coronary Artery Bypass Surgery

This randomized and prospective trial aims to evaluate the implementation of a rapid recovery protocol for coronary artery bypass grafting (CABG) in a hospital serving patients from the Brazilian Unified Health System (Sistema Único de Saúde - SUS). The study will compare outcomes between two groups: patients receiving care under the rapid recovery protocol and those following the standard institutional care. Primary Objective: Compare postoperative hospital stay between the rapid recovery group and the usual care group. Secondary Objectives: Assess morbidity and mortality between both groups. Evaluate patient satisfaction using validated tools. Analyze incremental costs associated with both approaches. Assess healthcare teams' learning progression regarding the protocol (Kirkpatrick method). Evaluate adherence to rapid recovery protocol metrics by healthcare teams. Measure changes in patient safety culture among healthcare professionals. Hypothesis: The null hypothesis assumes no difference in hospital stay between the two groups. The alternative hypothesis suggests that the rapid recovery protocol will reduce hospital stay compared to the standard care. Previous findings from Mejia et al. (2022) indicated a 40% reduction in postoperative hospital stay (from 13 to 7.8 days) for cardiac surgery patients under a rapid recovery protocol at the Heart Institute (InCor HCFMUSP). This trial will provide critical insights into the applicability of enhanced recovery after surgery (ERAS) principles in cardiac surgery within the context of public healthcare, aiming to improve outcomes and optimize resource use.

Participants needed: 128
Trial details
Biological sex: AllType: InterventionalSponsor: University of Sao Paulo General HospitalUpdated: Dec 3, 2024Locations: 1
Eligibility criteria

Adult patients (>18 years old) [+2]

Emergency patients [+7]