Optimizing the Care Pathway of Febrile Children Via Capillary C-reactive Protein Assay in Primary Care

ConditionFever
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age3-15
SponsorCentre Hospitalier Universitaire de Nīmes

About this trial

Fever is the leading reason for outpatient consultations among children aged 2 to 9 years. The main concern in fever is severe bacterial infection, particularly for younger children. History and clinical examination do not always differentiate viral infections from bacterial infection. In 20% of febrile children, no infectious focus is found after examination and additional tests are necessary. The first one is measuring C-reactive protein (CRP). The results are obtained in several hours on an outpatient basis, causing long delays before starting treatment and often requiring telephone calls or further consultations. Emergency room use is constantly increasing, generating growing tensions within healthcare facilities, yet a large number of visits are avoidable. Among children visiting the pediatric emergency room, parents reported being referred by their primary care physician in approximately 20% of cases for children aged 1 to 5 years and in 30% of cases for children under one year old. The use of capillary medical device to measure CRP in primary care could reduce this referral rate and help relieve overcrowding in emergency rooms, as well as unscheduled consultation centers and medical analysis laboratories. This would result in a streamlined care pathway, saving time for both physicians and patients, as well as reducing the cost of care for the healthcare system.

Eligibility criteria

Qualifiers

The patient must be a member or beneficiary of a health insurance plan

Fever > 12h in infants aged 3 to 6 months

Fever ≥ 5 days in children over 6 months of age

Fever >12h regardless of age, and at the time of consultation, the doctor is concerned about the child's general condition, the tolerance of the fever, or doubts about a bacterial focus (e.g. suspicion of pneumopathy, appendicitis, etc.).

Disqualifiers

The subject is participating in a category 1 interventional study, or a study with drug or medical device

Premature infants under one year of age

Immunosuppression

Sunstroke

Trial design

Treatments tested in this trial

  • Capillary CRP

Treatment groups

420 Participants
are divided into 2 treatment groups