Oropharyngeal Candidiasis (OPC) and S-ECC
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age9-15
SponsorTemple University
About this trial
The overall objective of this study is to investigate the association of early Candida infection (known as oral thrush or oropharyngeal candidiasis, OPC) in children during the first year of life with the onset and severity of severe early childhood caries (S-ECC).
Eligibility criteria
Qualifiers
Male or female individuals at the age of 9-15-month-old
Must have at least one fully erupted tooth at baseline visit
Parent/guardian willing and able to provide informed consent
With or without a history of OPC (the study team will enroll 35 participants with and 35 participants without a history of OPC)
Disqualifiers
Presence of a systemic medical condition (e.g. Down syndrome etc.)
Presence of an orofacial deformity
Presence of dental caries
Use of systemic antimicrobial therapy within 30 days of the baseline visit
Trial design
Treatments tested in this trial
- Not listed
Trial groups
70 Participants
are grouped into 2 trial groupsSponsors and collaborators
Temple University
Lead sponsor
Children's Hospital of Philadelphia
Collaborator
Source ClinicalTrials.gov