Outcomes of Uretheroileal Suspension Technique During Open Radical Cystectomy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorSohag University

About this trial

The suspension technique is reported as the puboprostatic ligaments that attach the prostate to the symphysis pubis. After the ligating the complex, including both the dorsal vein complex and the puboprostatic ligaments, this complex was sharply divided anteriorly from the prostate with a safe distance (1-2 mm), and the urethra is defined and divided. After removing the prostate, the ileal pouch is reconstructed by completely everting the mucosa and sutured outward with a running 4-0 absorbable suture around the edge. The neck of the neobladder was narrowed to ≈1 cm, for convenient passage of a 20 F catheter. Anastomotic sutures of 3-0 absorbable polyglactin were placed at the 1, 3, 5, 6, 7, 9, 11 and 12 o'clock positions

Eligibility criteria

Qualifiers

Patient age >18 years.

Muscle-invasive bladder carcinoma (MIBC).

- (recurrent disease that is unresponsive to other treatments

- high-grade tumors (T1, carcinoma in situ) refractory to intravesical therapy

Disqualifiers

NMIBC or benign disease.

Severe hepatic renal dysfunction.

Urethral involvement with bladder carcinoma.

Poor overall health status.

Trial design

Treatments tested in this trial

  • suspension uretheroileal technique
  • conventional radical cystectomy and ileal neobladder

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators