Oxygen Reserve Index (ORi) in Identifying Desaturation
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorIstanbul University
About this trial
This randomized clinical trial investigates whether Oxygen Reserve Index (ORi) monitoring enables earlier detection of impending hypoxemia compared with conventional pulse oximetry during apneic intermittent ventilation in adult patients undergoing endolaryngeal surgery under general anesthesia. By providing continuous, noninvasive assessment of oxygen reserve in the hyperoxic range, ORi may offer an earlier warning of oxygen depletion before peripheral oxygen saturation declines. The study compares time to reventilation thresholds, arterial blood gas parameters, and perioperative respiratory outcomes between ORi-guided and standard SpO₂-guided monitoring strategies.
Eligibility criteria
Qualifiers
Age 18 years or older
Scheduled for elective endolaryngeal surgery
Planned general anesthesia with apneic intermittent ventilation
American Society of Anesthesiologists (ASA) physical status I-III
Disqualifiers
Age under 18 years
Preoperative chronic hypoxemia (baseline SpO₂ < 95%)
Patients transferred from the intensive care unit
ASA physical status IV or higher
Trial design
Treatments tested in this trial
- oxygen monitoring techniques
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov