Periodontal Disease and Salivary Mitofusin Levels
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorErzincan University
About this trial
The aim of this observational study is to find out whether there is a level difference in salivary mitofusin-1 and mitofusin-2 levels due to changes in periodontal status. The main question it aims to answer is:
* Do salivary mitofusin-1 and mitofusin-2 levels of periodontitis patients differ from healthy patients? * Could salivary mitofusin-1 and mitofusin-2 levels be biomarkers for periodontal disease?
Biochemical analysis will be performed on saliva samples taken at once from gingivitis or periodontitis patients and healthy individuals who apply to the periodontology clinic, at the initial stage of the treatment. There is no ongoing monitoring or second sampling.
Eligibility criteria
Qualifiers
Being between the ages of 18 and 65.
Willing to participate in the study and provide a saliva sample.
Having a healthy periodontal condition, gingivitis, or periodontitis (Stage 3-4, Grade C).
Having fasted from any food or drink (except water) for the past 2 hours prior to providing the saliva sample.
Disqualifiers
Having used antibiotics within the last 6 months.
Having received periodontal treatment within the last 6 months.
Having fewer than 20 teeth (excluding third molars).
Having any systemic diseases.
Trial design
Treatments tested in this trial
- Biochemical analysis of saliva sample
Treatment groups
81 Participants
are divided into 3 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov