The aim of this clinical trial is to evaluate anti-inflammatory effect of various intracanal medications:
1. Calcium Hydroxide Slurry mixed with 3% Sodium Hypochlorite 2. Calcium Silicate 3. Calcium Hydroxide
In retreatment cases in terms of:
1. Biological Evaluation: Biomarker (IL 1B) 2. Radiographic Evaluation: CBCT 3. Clinical Evaluation: Pain Score (VAS)
Age: 21-45 years.
Medically free patients. (ASA Class 1)
Gender: males and females
Patients who are cooperative at operation and in attendance at scheduled follow-up visits.
Patients with a history of allergic reactions to any of the study materials.
Teeth that become non-restorable after complete caries excavation.
Teeth that have mobility or deep periodontal pockets.
Teeth with internal or external resorption.