Periapical Abscess

2

Review clinical trials related to Periapical Abscess. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Biological, Radiographic and Clinical Evaluation of Various Inter-Visit Root Canal Dressings in Retreatment Cases

The aim of this clinical trial is to evaluate anti-inflammatory effect of various intracanal medications: 1. Calcium Hydroxide Slurry mixed with 3% Sodium Hypochlorite 2. Calcium Silicate 3. Calcium Hydroxide In retreatment cases in terms of: 1. Biological Evaluation: Biomarker (IL 1B) 2. Radiographic Evaluation: CBCT 3. Clinical Evaluation: Pain Score (VAS)

Participants needed: 60
Trial details
Phase: Phase 1Age: 21-45Biological sex: AllType: InterventionalSponsor: Ain Shams UniversityUpdated: Jun 12, 2026Locations: 1
Eligibility criteria

Age: 21-45 years. [+5]

Patients with a history of allergic reactions to any of the study materials. [+3]

Status: Not yet recruiting

Using Platelet-rich Fibrin in Regenerative Endodontic Treatment in Mature Permanent Teeth

This study aims to evaluate the antibacterial effects of injectable platelet-rich fibrin (i-PRF) in vitro, and to assess the clinical and radiographic outcomes of using advanced platelet-rich fibrin (A-PRF+) and i-PRF in regenerative endodontic treatment of mature permanent teeth with necrotic pulp. The study will compare the effectiveness of PRF-based treatment with conventional blood clot-based regenerative endodontics.

Participants needed: 57
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of Medicine and Pharmacy at Ho Chi Minh CityUpdated: Sep 25, 2025Locations: 1
Eligibility criteria

The tooth has had previous endodontic treatment. [+9]