The goal of this NIH-sponsored study is to characterize three biomarkers derived from 129Xe gas exchange MRI and to understand how they change in response to interventions.
Outpatients of either gender, age > 18
Willing and able to give informed consent and adhere to visit/protocol (Consent must be given before any study procedures are performed.)
Subject has no diagnosed pulmonary conditions
Subject has not smoked in the previous 5 years
MRI is contraindicated based on responses to MRI screening questionnaire
Subject is pregnant or lactating
Resting O2 saturation <90% with maximum supplemental O2 delivered by nasal canula
Respiratory illness of a bacterial or viral etiology within 30 days of MRI
Bastiaan Driehuys
Lead sponsor
Duke University
Sponsor institution
National Institutes of Health (NIH)
Collaborator