Brimonidine Eye Drops in the Prevention of Myopia Progression

ConditionMyopia
Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age6-14
SponsorFundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal

About this trial

Study to determine the efficacy of alpha-2 adrenergic drugs (brimonidine) in the prevention of myopia progression. Given that the drugs used so far have limited efficacy and side effects (loss of near vision, photophobia), it may be an interesting contribution to such treatment at low cost, and to avoid the expense of managing the complications of myopia that develop throughout life.

Eligibility criteria

Qualifiers

Age ≥ 6 to ≤ 14 years

Patients who, after having received information about the design, the purposes of the study, the possible risks that may arise from it and that at any time they may refuse to cooperate, give written consent to participate in the study (the patient older than 12 years and the legal representative)

Myopia ≥ -1. 50 Diopters of spherical equivalent, ranging from -1.50 to -5.50 D

Astigmatism with a cylinder power ≤ -1.50 Diopters

Disqualifiers

Presence of any other ocular pathology (other than myopia)

History of allergy to the medications and excipients used in the study

History of previous therapy for myopia using eye drops, contact lenses or multifocal or bifocal glasses

Amblyopia (2 or more lines of difference in visual acuity between both eyes, on logMAR scale, with optical correction)

Trial design

Treatments tested in this trial

  • Treatment with brimonidine eye drops 0.025%

Treatment groups

40 Participants
are divided into 1 treatment group