About this trial
Endoscopic sinus surgery (ESS) is a common otolaryngologic procedure that aims to remove the partitions that separate the sinus cavities, remove inflamed tissue, and optimize the sinuses for topical medication use. In this procedure, the surgeon will inject a combination of drugs, local anesthetics, and vasoconstrictors, to reduce bleeding and improve visualization. However, previous studies have shown similar results when injected with only saline. In this study, investigators want to determine if the injection of local anesthesic+vasoconstrictor compared to no injection at all makes any difference in improving the surgeon's visualization during an ESS.
Eligibility criteria
Qualifiers
Age 19 years or older
Scheduled for primary ESS (including septoplasty)
Disqualifiers
Cystic fibrosis
Systemic vasculitis or any bleeding disorders
Known or suspected hypersensitivity to bupivacaine or epinephrine
Previous sinus surgery
Trial design
Treatments tested in this trial
- Sensorcaine with Epinephrine
- Sham injection
Treatment groups
Sponsors and collaborators
Amin Javer
Lead sponsor
St. Paul's Hospital, Canada
Sponsor institution