Sinus Disease

2

Review clinical trials related to Sinus Disease. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Prospective Study of Sinonasal and Skull-base Tumours Management

This observational prospective clinical study aims to describe the epidemiology, management and outcome of patients with sinonasal and skull-base pathology (tumours and diseases with malignant clinical characteristics) in a tertiary otorhinolaryngology referral centre. The main questions it aims to answer are: * what is the caseload of patients with the included pathology in our centre * what are the results of management of these cases * what are the epidemiological characteristics of included patients * what is the quality of life of included patients.

Participants needed: 120
Trial details
Biological sex: AllType: ObservationalSponsor: University Medical Centre LjubljanaUpdated: Apr 29, 2026Locations: 1Duration: 5 Years
Eligibility criteria

sinonasal and/or skull-base cancer [+2]

lateral skull-base disease primarily originating in the temporal bone and withou...

Status: Recruiting

Bupivacaine and Epinephrine Injection Study

Endoscopic sinus surgery (ESS) is a common otolaryngologic procedure that aims to remove the partitions that separate the sinus cavities, remove inflamed tissue, and optimize the sinuses for topical medication use. In this procedure, the surgeon will inject a combination of drugs, local anesthetics, and vasoconstrictors, to reduce bleeding and improve visualization. However, previous studies have shown similar results when injected with only saline. In this study, investigators want to determine if the injection of local anesthesic+vasoconstrictor compared to no injection at all makes any difference in improving the surgeon's visualization during an ESS.

Participants needed: 80
Trial details
Phase: Phase 2, Phase 3Age: 19+Biological sex: AllType: InterventionalSponsor: Amin JaverUpdated: May 15, 2025Locations: 1
Eligibility criteria

Age 19 years or older [+1]

Cystic fibrosis [+8]