Effect of Add-on L-Arginine Therapy on Heart Failure Patients

ConditionHeart Failure
Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age19+
SponsorGerman University in Cairo

About this trial

Heart failure is considered one of the greatest challenges globally. There are various treatment strategies for heart failure. L-Arginine is an amino acid that was found to have beneficial effect on vasculature. This study aims to study the benefits and side effects of using L-arginine on the patients with ejection fraction \<40%

Eligibility criteria

Qualifiers

Patients with EF <40%

eGFR >30 mL/min/1.73 m2

Stable patients

Capable and willing to provide written consent

Disqualifiers

Patients with implantable cardioverter-defibrillator

Pregnant or lactating fmeales

Patients with a history of sensitivity to L-Arginine or any of the excipients

Acute heart failure patients

Trial design

Treatments tested in this trial

  • L-Arginine Powder
  • Placebo

Treatment groups

200 Participants
are divided into 2 treatment groups

Sponsors and collaborators

German University in Cairo

Lead sponsor

Ain Shams University

Collaborator