Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Effect of Add-on L-Arginine Therapy on Heart Failure Patients

Heart failure is considered one of the greatest challenges globally. There are various treatment strategies for heart failure. L-Arginine is an amino acid that was found to have beneficial effect on vasculature. This study aims to study the benefits and side effects of using L-arginine on the patients with ejection fraction \<40%

Participants needed: 200
Trial details
Phase: Phase 2Age: 19+Biological sex: AllType: InterventionalSponsor: German University in CairoUpdated: Feb 6, 2026Locations: 1
Eligibility criteria

Patients with EF <40% [+3]

Patients with implantable cardioverter-defibrillator [+5]

Status: Recruiting

Evaluation of the Effect of L-Arginine on the Cognitive Function in Geriatric Patients

This study aims to evaluate the effect of L-arginine supplementation on cognitive function in geriatric patients. Eligible participants will receive either L-arginine (6 grams once daily) or placebo, and their cognitive performance will be assessed using validated cognitive assessment tools over the study period. The participants will receive the intervention for 4 weeks and followed up every 2 weeks. The primary outcome is improvement in cognitive function, while secondary outcomes include safety, tolerability, and quality of life measures. The findings may provide evidence for the potential role of L-arginine in supporting cognitive health in elderly populations.

Participants needed: 60
Trial details
Phase: Phase 2Age: 60+Biological sex: AllType: InterventionalSponsor: German University in CairoUpdated: Jan 21, 2026Locations: 1
Eligibility criteria

Age >60 years [+1]

Presence of neurodegenerative diseases (e.g.: Alzheimer's disease, Parkinson's d... [+11]

Status: Recruiting

L-carnitine Supplementation in Rheumatoid Arthritis Patients

This study aims to evaluate the effect of l-carnitine as add- on therapy for improving the outcome in rheumatoid arthritis patients.

Participants needed: 60
Trial details
Phase: Phase 2Age: 18-60Biological sex: AllType: InterventionalSponsor: German University in CairoUpdated: Jan 7, 2025Locations: 1
Eligibility criteria

age between 18-60 years old [+4]

pregnant or lactating female [+5]

Status: Not yet recruiting

Effect of Vitamin D Supplementation on Mental Health: An Exploratory Study on A University Students Suffering From Vitamin D Deficiency

University students are susceptible to psychological burdens such as depressive symptoms, anxiety, and stress which might have been linked to vitamin D deficiency. Low serum vitamin D level is well recognized around the world. Vitamin D has been reported to modulate several neurological pathways in the brain that control psychological function. As a result, the purpose of this study is to evaluate the effect of vitamin D supplementation on the presence of depressive symptoms, anxiety, and stress in university students. The study will include two phases. The first phase is a cross-sectional phase assessing the prevalence vitamin D deficiency in addition to psychological symptoms. The second phase is a randomized controlled clinical trial that aims to assess the effect of vitamin D supplementation on the prevalent psychological symptoms and its impact on the academic performance among university students. The study will look at the relationship between mental health and vitamin D deficiency, as well as how it will affect academic performance of university students.

Participants needed: 70
Trial details
Phase: Phase 1, Phase 2Age: 18-22Biological sex: AllType: InterventionalSponsor: German University in CairoUpdated: Jun 13, 2024
Eligibility criteria

For phase 1: sample will be selected using convenient sampling method where all...

Hypersensitivity to oral vitamin D supplements such as Diviton or Vidrop. [+6]