This study will probe if the biological changes in amnestic mild cognitive impairment (aMCI) are related to a history of mild traumatic brain injury (mTBI) using high definition transcranial direct current stimulation (HD-tDCS) and blood-derived biomarker tools. Participants who Do as well as those who Do Not have a history of mTBI will be enrolled in the study.
Active diagnosis of amnestic mild cognitive impairment
Presence of an mTBI history for the mTBI+ group; absence of an mTBI history for a control sample
Female and male subjects
All races/ethnicities
Mild traumatic brain injury within past year
Lifetime history of moderate or severe brain injury
Lifetime major neurologic syndromes (e.g., stroke, epilepsy, brain tumor)
Lifetime major cardiovascular conditions (e.g., heart attack, heart failure)