About this trial
This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for post-stroke fatigue in people who have had a stroke more than six months prior to enrolling. Fatigue is a common condition after a stroke and can negatively impact an individual's ability to perform desired social and physical activities. Magnetic stimulation of the brain has been shown to improve signs and symptoms of related psychological (e.g., depression) conditions. Participants in this trial will receive a type of magnetic stimulation called repetitive transcranial magnetic stimulation, or rTMS. The investigators will measure feelings of fatigue and other clinical characteristics related to mood and cognition before and after participants receive rTMS.
Eligibility criteria
Qualifiers
34 - 80 years of age
more than 6 months post-stroke
Clinically present fatigue
Disqualifiers
Contraindications to MRI/TMS/rTMS (e.g. implanted metal within the head, history of seizures)
Inability to follow simple three-step instructions
Diagnosed comorbid neurological conditions (e.g. multiple sclerosis, Parkinson's disease, moderate/severe TBI)
Pregnancy
Trial design
Treatments tested in this trial
- High frequency repetitive transcranial magnetic stimulation
- Sham repetitive transcranial magnetic stimulation
Treatment groups
Sponsors and collaborators
VA Office of Research and Development
Lead sponsor
Joseph Maxwell Cleland VA Medical Center
Collaborator