About this trial
Pilot, single-site, prospective study of QLS-111 0.015 % in subjects with NPDR, OAG or NTG
Eligibility criteria
Qualifiers
Diagnosis of mild to moderate OAG, mild to moderate NTG, or stable NPDR in at least one eye.
Corrected visual acuity in each eye +1.0 logMAR or better by early treatment diabetic retinopathy study (ETDRS) in each eye (equivalent to 20/200).
Able and willing to give signed informed consent and follow study instructions.
Disqualifiers
History of active ocular disease other than mild to moderate OAG, mild to moderate NTG, or stable NPDR.
Patient is using more than 1 ocular hypotensive topical medication for intraocular pressure (IOP) control (prior MIGS and/or laser trabeculoplasty to control IOP is allowed if done at least 3 months from Screening (Visit 1).
Use of TO β-blockers (i.e. timolol) within 3 months prior to Screening.
Is noncompliant with current ocular anti-hypotensive medications and/or unwilling to be compliant throughout the study.
Trial design
Treatments tested in this trial
- QLS-111 Ophthalmic Solution (0.015%)
- QLS-111 Ophthalmic Solution (0.075%)