About this trial
This is a randomized, phase III, prospective, multi-center trial in newly diagnosed nasopharyngeal carcinoma (NPC) patients without distant metastasis. The aim of this study is to evaluate the efficacy and safety of modified IMRT, of which CTV delineation was only based on geometric expansion from GTV.
Eligibility criteria
Qualifiers
Pathologic diagnosis (pathologically confirmed by nasopharyngeal biopsy) was nasopharyngeal carcinoma;
No distant metastatic;
Patients with baseline MRI date of nasopharynx and neck, and completed the first course of treatment in our hospital;
Eastern Cooperative Oncology Group (ECOG) score of 0 or 1;
Disqualifiers
Disease progression during IMRT;
Previous malignancy or other concomitant malignant diseases;
The evaluation information of tumor efficacy can not be obtained;
Receive blind treatment in other clinical research;
Trial design
Treatments tested in this trial
- CTV Delineation Based on Geometric Expansion From GTV in Nasopharyngeal Carcinoma